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2ihc
From Proteopedia
(Difference between revisions)
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==Crystal structure of the bric-a-brac (BTB) domain of human BACH1== | ==Crystal structure of the bric-a-brac (BTB) domain of human BACH1== | ||
| - | <StructureSection load='2ihc' size='340' side='right' caption='[[2ihc]], [[Resolution|resolution]] 2.44Å' scene=''> | + | <StructureSection load='2ihc' size='340' side='right'caption='[[2ihc]], [[Resolution|resolution]] 2.44Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ihc]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2ihc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IHC FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACH1 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACH1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ihc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ihc OCA], [https://pdbe.org/2ihc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ihc RCSB], [https://www.ebi.ac.uk/pdbsum/2ihc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ihc ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/BACH1_HUMAN BACH1_HUMAN]] Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Amos, A L]] | [[Category: Amos, A L]] | ||
[[Category: Arrowsmith, C]] | [[Category: Arrowsmith, C]] | ||
Revision as of 11:16, 31 March 2021
Crystal structure of the bric-a-brac (BTB) domain of human BACH1
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Categories: Human | Large Structures | Amos, A L | Arrowsmith, C | Bullock, A | Bunkoczi, G | Delft, F von | Edwards, A | Gorrec, F | Knapp, S | Papagrigoriou, E | Structural genomic | Sundstrom, M | Turnbull, A P | Umeano, C | Weigelt, J | Bach1 | Bric-a-brac domain | Cap'n'collar type of basic region leucine zipper factor family | Protein-protein interaction | Sgc | Transcription | Transcription factor
