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2iir
From Proteopedia
(Difference between revisions)
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==Acetate kinase from a hypothermophile Thermotoga maritima== | ==Acetate kinase from a hypothermophile Thermotoga maritima== | ||
| - | <StructureSection load='2iir' size='340' side='right' caption='[[2iir]], [[Resolution|resolution]] 3.30Å' scene=''> | + | <StructureSection load='2iir' size='340' side='right'caption='[[2iir]], [[Resolution|resolution]] 3.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2iir]] is a 10 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2iir]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IIR FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g99|1g99]], [[1tuu|1tuu]], [[1tuy|1tuy]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1g99|1g99]], [[1tuu|1tuu]], [[1tuy|1tuy]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ack ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ack ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Acetate_kinase Acetate kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.1 2.7.2.1] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iir OCA], [https://pdbe.org/2iir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iir RCSB], [https://www.ebi.ac.uk/pdbsum/2iir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iir ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ACKA_THEMA ACKA_THEMA]] Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Phosphorylates propionate (54%) in addition to acetate (100%). Uses GTP (100%), ITP (163%), UTP (56%), and CTP (21%) as phosphoryl donors in addition to ATP (100%).<ref>PMID:10074080</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/2iir_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/2iir_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: Acetate kinase]] | [[Category: Acetate kinase]] | ||
[[Category: Atcc 43589]] | [[Category: Atcc 43589]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Hasson, M S]] | [[Category: Hasson, M S]] | ||
[[Category: Mukhopadhyay, S]] | [[Category: Mukhopadhyay, S]] | ||
Revision as of 11:16, 31 March 2021
Acetate kinase from a hypothermophile Thermotoga maritima
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