2ix7
From Proteopedia
(Difference between revisions)
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==Structure of apo-calmodulin bound to unconventional myosin V== | ==Structure of apo-calmodulin bound to unconventional myosin V== | ||
- | <StructureSection load='2ix7' size='340' side='right' caption='[[2ix7]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='2ix7' size='340' side='right'caption='[[2ix7]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2ix7]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2ix7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IX7 FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYS:CYSTEINE'>CYS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYS:CYSTEINE'>CYS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ix7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ix7 OCA], [https://pdbe.org/2ix7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ix7 RCSB], [https://www.ebi.ac.uk/pdbsum/2ix7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ix7 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/MYO5A_MOUSE MYO5A_MOUSE]] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.<ref>PMID:22908308</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
- | *[[Calmodulin|Calmodulin]] | + | *[[Calmodulin 3D structures|Calmodulin 3D structures]] |
- | *[[Myosin|Myosin]] | + | *[[Myosin 3D Structures|Myosin 3D Structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Cohen, C]] | [[Category: Cohen, C]] |
Revision as of 11:23, 31 March 2021
Structure of apo-calmodulin bound to unconventional myosin V
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Categories: Large Structures | Lk3 transgenic mice | Cohen, C | Gaucher, J F | Houdusse, A | Krementsova, E | Mui, S | Trybus, K M | Acetylation | Actin-binding | Atp-binding | Ca2+ regulation | Calcium | Calmodulin | Calmodulin-binding | Coiled coil | Complex | Contractile protein | Contractile protein-metal binding complex | Contractile protein/metal binding | Iq motif | Metal binding | Methylation | Motor protein | Myosin | Nucleotide- binding | Phosphorylation | Ubl conjugation