Nuclear receptors
From Proteopedia
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E: Ligand binding domain (LBD) containing an <scene name='54/543362/Cv/3'>active site</scene> which binds intramolecularly the N-terminal FXXFL motif or coactivators with the same motif (Human androgen receptor ligand-binding domain complex with modulator; PDB code [[3b5r]]).<ref>PMID:18805694</ref> Water molecules are shown as red spheres. <br /> | E: Ligand binding domain (LBD) containing an <scene name='54/543362/Cv/3'>active site</scene> which binds intramolecularly the N-terminal FXXFL motif or coactivators with the same motif (Human androgen receptor ligand-binding domain complex with modulator; PDB code [[3b5r]]).<ref>PMID:18805694</ref> Water molecules are shown as red spheres. <br /> | ||
F: C-terminal domain | F: C-terminal domain | ||
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| + | See also [[Receptor]] | ||
'''Family members (~ according to [https://en.wikipedia.org/wiki/Nuclear_receptor]):''' | '''Family members (~ according to [https://en.wikipedia.org/wiki/Nuclear_receptor]):''' | ||
Revision as of 13:22, 4 April 2021
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References
- ↑ Bohl CE, Wu Z, Chen J, Mohler ML, Yang J, Hwang DJ, Mustafa S, Miller DD, Bell CE, Dalton JT. Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5567-70. Epub 2008 Sep 5. PMID:18805694 doi:10.1016/j.bmcl.2008.09.002
- ↑ Li MJ, Greenblatt HM, Dym O, Albeck S, Pais A, Gunanathan C, Milstein D, Degani H, Sussman JL. Structure of estradiol metal chelate and estrogen receptor complex: The basis for designing a new class of selective estrogen receptor modulators. J Med Chem. 2011 Apr 7. PMID:21473635 doi:10.1021/jm200192y
