User:Brianna Avery/Sandbox 1
From Proteopedia
(Difference between revisions)
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===Significance=== | ===Significance=== | ||
| - | ====Stearoyl-CoA Desaturase is an enzyme which speeds up desaturation of a double bond within a fatty acid hydrocarbon chain. The addition of a double bond is necessary for the biosynthesis of monounsaturated fatty acids such as: cholesterol, phospholipids, and triglycerides. Functioning SCD creates the balance between the accumulation and use of fats in the body. Inhibition of SCD leads to possible treatment of metabolic disease and cancer.==== | + | =====Stearoyl-CoA Desaturase is an enzyme which speeds up desaturation of a double bond within a fatty acid hydrocarbon chain. The addition of a double bond is necessary for the biosynthesis of monounsaturated fatty acids such as: cholesterol, phospholipids, and triglycerides. Functioning SCD creates the balance between the accumulation and use of fats in the body. Inhibition of SCD leads to possible treatment of metabolic disease and cancer.===== |
===Desaturation Mechanism=== | ===Desaturation Mechanism=== | ||
Revision as of 17:40, 5 April 2021
Stearoyl-CoA Desaturase 1/ SCD1
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References
- ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
Student Contributors
- Brianna M. Avery
- William J. Harris III
- Emily M. Royston
