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2k2s
From Proteopedia
(Difference between revisions)
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==structure of the MIC1-GLD/MIC6-EGF complex from Toxoplasma gondii== | ==structure of the MIC1-GLD/MIC6-EGF complex from Toxoplasma gondii== | ||
| - | <StructureSection load='2k2s' size='340' side='right' caption='[[2k2s]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''> | + | <StructureSection load='2k2s' size='340' side='right'caption='[[2k2s]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2k2s]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2k2s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxgo Toxgo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K2S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K2S FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2k2t|2k2t]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2k2t|2k2t]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MIC1 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MIC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 TOXGO]), MIC6 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 TOXGO])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k2s OCA], [https://pdbe.org/2k2s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k2s RCSB], [https://www.ebi.ac.uk/pdbsum/2k2s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k2s ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/MIC1_TOXGO MIC1_TOXGO]] Adhesin. Required for attachment of the parasite to the host cell prior to invasion. Ensures correct folding of MIC6 and transport of the MIC6-MIC1-MIC4 complex into the micronemes.<ref>PMID:11447133</ref> <ref>PMID:11157983</ref> <ref>PMID:16166092</ref> <ref>PMID:17491595</ref> <ref>PMID:9027753</ref> [[https://www.uniprot.org/uniprot/MIC6_TOXGO MIC6_TOXGO]] Escorter protein required for import of MIC1 and MIC4 adhesins into the microneme.<ref>PMID:11157983</ref> <ref>PMID:16166092</ref> <ref>PMID:18818666</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Toxgo]] | [[Category: Toxgo]] | ||
[[Category: Matthews, S]] | [[Category: Matthews, S]] | ||
Revision as of 08:07, 7 April 2021
structure of the MIC1-GLD/MIC6-EGF complex from Toxoplasma gondii
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