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2ke3
From Proteopedia
(Difference between revisions)
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==PC1/3 DCSG sorting domain in CHAPS== | ==PC1/3 DCSG sorting domain in CHAPS== | ||
| - | <StructureSection load='2ke3' size='340' side='right' caption='[[2ke3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2ke3' size='340' side='right'caption='[[2ke3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ke3]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2ke3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KE3 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Pcsk1, Att-1, Nec-1, Nec1 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Pcsk1, Att-1, Nec-1, Nec1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Proprotein_convertase_1 Proprotein convertase 1], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.93 3.4.21.93] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ke3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ke3 OCA], [https://pdbe.org/2ke3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ke3 RCSB], [https://www.ebi.ac.uk/pdbsum/2ke3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ke3 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/NEC1_MOUSE NEC1_MOUSE]] Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Proprotein convertase 1]] | [[Category: Proprotein convertase 1]] | ||
Revision as of 08:18, 7 April 2021
PC1/3 DCSG sorting domain in CHAPS
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Categories: Large Structures | Lk3 transgenic mice | Proprotein convertase 1 | Dikeakos, J D | Ghirlando, R | Lacombe, M J | Legault, P | Lello, P Di | Omichinski, J G | Reudelhuber, T L | Calcium | Cleavage on pair of basic residue | Cytoplasmic vesicle | Glycoprotein | Hydrolase | Prohormone convertase | Protease | Secretory granule | Serine protease | Zymogen

