3lon
From Proteopedia
(Difference between revisions)
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==HCV NS3-4a protease domain with ketoamide inhibitor narlaprevir== | ==HCV NS3-4a protease domain with ketoamide inhibitor narlaprevir== | ||
| - | <StructureSection load='3lon' size='340' side='right' caption='[[3lon]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='3lon' size='340' side='right'caption='[[3lon]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3lon]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3lon]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LON FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=NNA:(1R,2S,5S)-3-[N-({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)-3-methyl-L-valyl]-N-{(1S)-1-[(1R)-2-(cyclopropylamino)-1-hydroxy-2-oxoethyl]pentyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide'>NNA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=NNA:(1R,2S,5S)-3-[N-({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)-3-methyl-L-valyl]-N-{(1S)-1-[(1R)-2-(cyclopropylamino)-1-hydroxy-2-oxoethyl]pentyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide'>NNA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NS3 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NS3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31646 Hepatitis C virus subtype 1a])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lon OCA], [https://pdbe.org/3lon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lon RCSB], [https://www.ebi.ac.uk/pdbsum/3lon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lon ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Virus protease 3D structures|Virus protease 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Hepatitis c virus subtype 1a]] | [[Category: Hepatitis c virus subtype 1a]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Prongay, A J]] | [[Category: Prongay, A J]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
Revision as of 06:49, 14 April 2021
HCV NS3-4a protease domain with ketoamide inhibitor narlaprevir
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Categories: Hepatitis c virus subtype 1a | Large Structures | Prongay, A J | Atp-binding | Capsid protein | Envelope protein | Helicase | Hepatitis c virus | Host membrane | Hydrolase | Macrocyclic ketoamide inhibitor | Membrane | Ns3 protease domain | Nucleotide-binding | Rna replication | Serine protease | Transmembrane | Viral protein | Viral protein-inhibitor complex | Virion
