1js3

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<StructureSection load='1js3' size='340' side='right'caption='[[1js3]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='1js3' size='340' side='right'caption='[[1js3]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1js3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JS3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1js3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JS3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=142:CARBIDOPA'>142</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=142:CARBIDOPA'>142</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1js6|1js6]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1js6|1js6]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aromatic-L-amino-acid_decarboxylase Aromatic-L-amino-acid decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.28 4.1.1.28] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aromatic-L-amino-acid_decarboxylase Aromatic-L-amino-acid decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.28 4.1.1.28] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1js3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1js3 OCA], [http://pdbe.org/1js3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1js3 RCSB], [http://www.ebi.ac.uk/pdbsum/1js3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1js3 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1js3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1js3 OCA], [https://pdbe.org/1js3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1js3 RCSB], [https://www.ebi.ac.uk/pdbsum/1js3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1js3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DDC_PIG DDC_PIG]] Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
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[[https://www.uniprot.org/uniprot/DDC_PIG DDC_PIG]] Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Carbidopa|Carbidopa]]
 
*[[DOPA decarboxylase|DOPA decarboxylase]]
*[[DOPA decarboxylase|DOPA decarboxylase]]
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*[[User:Brian Hernandez/DOPA Decarboxylase|User:Brian Hernandez/DOPA Decarboxylase]]
 
== References ==
== References ==
<references/>
<references/>

Revision as of 07:21, 14 April 2021

Crystal structure of dopa decarboxylase in complex with the inhibitor carbidopa

PDB ID 1js3

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