Sandbox Reserved 1672

This protein has 2 large beta-sheets and 4 alpha-helices. The , binds with beta-sheet A. Beta sheet A also contains most of the catalytic amino acids.

Function of your protein

Alginate lyase, AlyC3, comes from the Psychromonas organism.

The function of AlyC3 is to degrade alginate. AlyC3 plays a role in b-elimination at the glycosidic 1,4-O link. This generates oligosaccharides or monosaccharides.

• insert rotating image of AlyC3 as a cartoon*

The known substrate for AlyC3 is polymannuronate.

Biological relevance and broader implications

. Alginate lyases are promising enzymes for the treatment of chronic lung infection by Pseudomonas aeruginosa (9). The synergistic action of endoand exolytic alginate lyases have remarkable potential for the production of biofuels by deconstructing the alginate-rich algal cell walls into monosaccharides (10, 11). Therefore, research on the characteristics and molecular catalytic mechanisms of alginate lyases is important to understand the degradation and recycling of alginate in the ocean and to facilitate the development of their industrial applications.

Important amino acids

Structural highlights

Other important features

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