Monoclonal Antibodies 3D structures

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Line 8: Line 8:
*Human Fab
*Human Fab
-
**[[3n9g]], [[3giz]], [[3eo9]], [[1ad9]], [[2fb4]], [[2ig2]], [[1qlr]], [[2zkh]], [[1qbl]], [[1igi]], [[5nst]] – hFab mAb - human<br />
+
**[[3n9g]], [[3giz]], [[3eo9]], [[1ad9]], [[2fb4]], [[2ig2]], [[1qlr]], [[2zkh]], [[1qbl]], [[1igi]], [[5nst]], [[6amj]], [[6cr1]], [[6h9x]], [[6rco]], [[6rcq]], [[6rcs]], [[6tcm]], [[6tcn]], [[6umh]], [[6umi]], [[6umj]] – hFab mAb - human<br />
-
**[[3qhz]], [[4fql]], [[4gxv]] - hFab anti-influenza<br />
+
**[[6amm]], [[6anp]], [[6ao0]], [[6tcp]], [[6tcq]] – hFab (mutant)<br />
 +
**[[3qhz]], [[4fql]], [[4gxv]], [[6btj]] - hFab anti-influenza<br />
**[[3qhf]] – hFab anti-influenza (mutant)<br />
**[[3qhf]] – hFab anti-influenza (mutant)<br />
**[[3qct]] – hFab anti-lysophosphatidic acid<br />
**[[3qct]] – hFab anti-lysophosphatidic acid<br />
-
**[[3inu]] – hFab anti-Ebola<br />
+
**[[3inu]], [[6n7u]] – hFab anti-Ebola<br />
**[[5jrp]] – hFab anti-Marburg virus<br />
**[[5jrp]] – hFab anti-Marburg virus<br />
-
**[[3u6r]], [[1nlb]] – hFab anti-Hepatitis<br />
+
**[[3u6r]], [[1nlb]], [[6meg]], [[6med]], [[6mee]], [[6mef]], [[6wo5]] - hFab anti-hepatitis C virus<br />
**[[1b4j]] - hFab anti-γ- interferon<br />
**[[1b4j]] - hFab anti-γ- interferon<br />
 +
**[[6w73]] - hFab anti-CD4<br />
 +
**[[6al4]] - hFab anti-CD19<br />
**[[1bey]], [[1bfo]] - hFab anti-CD52<br />
**[[1bey]], [[1bfo]] - hFab anti-CD52<br />
**[[1t3f]] - hFab anti-IFN-γ<br />
**[[1t3f]] - hFab anti-IFN-γ<br />
**[[1x9q]] - hFab anti-fluorescin<br />
**[[1x9q]] - hFab anti-fluorescin<br />
**[[2d7t]] - hFab anti-hydroxybutyrate<br />
**[[2d7t]] - hFab anti-hydroxybutyrate<br />
-
**[[2fjf]] - hFab anti-VEGF<br />
+
**[[2fjf]], [[7lsi]] - hFab anti-VEGF<br />
**[[2gjj]] - hFab anti-ERBB-2<br />
**[[2gjj]] - hFab anti-ERBB-2<br />
**[[4g6k]] - hFab anti-interleukin-1<br />
**[[4g6k]] - hFab anti-interleukin-1<br />
Line 33: Line 36:
**[[4k7p]] – hFab rhumab6 + mFab 10C4<br />
**[[4k7p]] – hFab rhumab6 + mFab 10C4<br />
**[[6hud]] – hFab anti-amyloidosis – Cryo EM<br />
**[[6hud]] – hFab anti-amyloidosis – Cryo EM<br />
 +
**[[7k3q]] - hFab anti-SARS <br />
 +
**[[6srv]], [[6srx]], [[6ss0]], [[6tul]] - hFab anti-arginase <br />
 +
**[[6e65]] – hFab anti-malaria<br />
 +
**[[6u1t]] - mFab anti-Nipa virus<br />
*Mouse Fab
*Mouse Fab
Line 79: Line 86:
**[[3ojd]] – mFab anti-indolicidin<br />
**[[3ojd]] – mFab anti-indolicidin<br />
**[[6bpb]], [[6bpd]] – mFab anti-Vivax invasion<br />
**[[6bpb]], [[6bpd]] – mFab anti-Vivax invasion<br />
-
**[[3gk8]], [[1m71]], [[12e8]], [[1yuh]], [[1fgn]], [[1a6t]], [[4isv]], [[4jj5]], [[3gnm]], [[1ae6]], [[3c5s]], [[1mam]], [[3vg0]], [[4kph]], [[1mlb]], [[2vl5]], [[1rmf]], [[2adg]], [[1s5i]], [[1f8t]], [[4dvb]], – mFab <br />
+
**[[3gk8]], [[1m71]], [[12e8]], [[1yuh]], [[1fgn]], [[1a6t]], [[4isv]], [[4jj5]], [[3gnm]], [[1ae6]], [[3c5s]], [[1mam]], [[3vg0]], [[4kph]], [[1mlb]], [[2vl5]], [[1rmf]], [[2adg]], [[1s5i]], [[1f8t]], [[4dvb]], [[6dc7]], [[6fab]], [[6lkt]], [[6wt3]], [[6y54]], [[7c95]] – mFab <br />
**[[3c08]], [[1yy8]] - mFab commercial<br />
**[[3c08]], [[1yy8]] - mFab commercial<br />
**[[6a76]] - mFab anti-ROBO1<br />
**[[6a76]] - mFab anti-ROBO1<br />
**[[6vrt]] - mFab anti-metal<br />
**[[6vrt]] - mFab anti-metal<br />
 +
**[[6fbj]] - mFab anti-matrix melalloproteinase<br />
 +
**[[6gxx]], [[6i1o]], [[6qu9]] - mFab anti-antitrypsin<br />
 +
**[[6dg2]] – mFab anti-Ebola<br />
 +
**[[6ltg]] – mFab anti-herpesvirus<br />
 +
**[[6d9g]] – mFab anti-serotonin transporter<br />
*Anti-HIV Fab
*Anti-HIV Fab
Line 91: Line 103:
**[[6nc3]], [[6nc2]] – hFab anti-HIV + glycoprotein gp120 + glycoprotein gp41 – Cryo EM<br />
**[[6nc3]], [[6nc2]] – hFab anti-HIV + glycoprotein gp120 + glycoprotein gp41 – Cryo EM<br />
**[[3w9e]] – hFab anti-HIV 2 + glycoprotein D <br />
**[[3w9e]] – hFab anti-HIV 2 + glycoprotein D <br />
-
**[[4jo1]], [[4jo2]], [[4jo3]], [[4jo4]] - Fab anti-HIV R56 + gp120 - rabbit<br />
+
**[[7kde]] – hFab anti-HIV + HIV protein – Cryo EM<br />
**[[3cle]], [[3clf]], [[3cmo]], [[1h3p]], [[3oz9]], [[1mf2]], [[1nld]], [[1bog]], [[3mnv]], [[1il1]] - mFab anti-HIV<br />
**[[3cle]], [[3clf]], [[3cmo]], [[1h3p]], [[3oz9]], [[1mf2]], [[1nld]], [[1bog]], [[3mnv]], [[1il1]] - mFab anti-HIV<br />
**[[1rzk]] – mFab anti-HIV + glycoprotein gp120 <br />
**[[1rzk]] – mFab anti-HIV + glycoprotein gp120 <br />
Line 98: Line 110:
**[[4jo1]], [[4jo2]], [[4jo3]], [[4jo4]] - rFab anti-HIV R56 + gp120 <br />
**[[4jo1]], [[4jo2]], [[4jo3]], [[4jo4]] - rFab anti-HIV R56 + gp120 <br />
**[[6did]] – rFab anti-HIV 10A + glycoprotein gp160 <br />
**[[6did]] – rFab anti-HIV 10A + glycoprotein gp160 <br />
 +
**[[6p62]] – rFab anti-HIV E70 + env NFL – Cryo EM<br />
* Other Fab
* Other Fab
**[[1it9]] - hmFab anti-hFAS<br />
**[[1it9]] - hmFab anti-hFAS<br />
 +
**[[6l8t]] - hmFab anti-hepatitis B<br />
**[[2hwz]] – hmFab MEDI-493<br />
**[[2hwz]] – hmFab MEDI-493<br />
 +
**[[6e64]] – raFab anti-malaria<br />
**[[4idl]] – LgFab anti-cholera toxin<br />
**[[4idl]] – LgFab anti-cholera toxin<br />
**[[1c5d]], [[1fn4]] – Fab anti-acetylcholine receptor - rat<br />
**[[1c5d]], [[1fn4]] – Fab anti-acetylcholine receptor - rat<br />
 +
**[[6e8v]] – bFab-1<br />
 +
**[[6e9g]] – bFab-2<br />
 +
**[[6e9h]] – bFab-3<br />
 +
**[[6e9i]] – bFab-4<br />
 +
**[[6e9k]] – bFab-5<br />
 +
**[[6e9q]] – bFab-6<br />
 +
**[[6e9u]] – bFab-7<br />
*Fab: small molecule complex
*Fab: small molecule complex
Line 127: Line 149:
**[[1keg]] - mFab anti-photoproduct + DNA<br />
**[[1keg]] - mFab anti-photoproduct + DNA<br />
**[[5cp3]] – mFab anti-sulfonamide 4C7 + sulfonamide<br />
**[[5cp3]] – mFab anti-sulfonamide 4C7 + sulfonamide<br />
 +
**[[6pyd]] - mFab anti-marinobufagenin + marinobufagenin <br />
*Fab: peptide complex
*Fab: peptide complex
Line 133: Line 156:
**[[6vn1]] – hFab + glycoprotein B peptide – Cryo EM<br />
**[[6vn1]] – hFab + glycoprotein B peptide – Cryo EM<br />
**[[6vjt]] – hFab + hepatitis B peptide<br />
**[[6vjt]] – hFab + hepatitis B peptide<br />
 +
**[[6wn4]] – hFab + lipase peptide<br />
 +
**[[6lra]] – hFab + tau peptide<br />
 +
**[[7c94]] – hFab + podoplanin peptide<br />
 +
**[[6b5l]], [[6b5m]], [[6b5n]], [[6b5o]], [[6b5p]], [[6b5r]], [[6b5s]], [[6b5t]], [[6pbv]], [[6pbw]] – hFab + CSP peptide<br />
**[[2osl]] – hmFab + CD20 peptide<br />
**[[2osl]] – hmFab + CD20 peptide<br />
**[[3o41]], [[3o45]] – mFab + fusion protein F1 peptide<br />
**[[3o41]], [[3o45]] – mFab + fusion protein F1 peptide<br />
Line 138: Line 165:
**[[3ixt]] - mFab commercial + peptide<br />
**[[3ixt]] - mFab commercial + peptide<br />
**[[3c09]], [[1yy9]] - mFab commercial + EGFR peptide<br />
**[[3c09]], [[1yy9]] - mFab commercial + EGFR peptide<br />
-
**[[2v17]] - mFab + τ protein peptide<br />
+
**[[2v17]], [[6dc8]], [[6dc9]], [[6dca]], [[6pxr]], [[6xli]] - mFab + tau peptide<br />
**[[2hkf]] – mFab + carbonic anhydrase peptide<br />
**[[2hkf]] – mFab + carbonic anhydrase peptide<br />
**[[2zpk]] – mFab + proteinase-activated receptor peptide<br />
**[[2zpk]] – mFab + proteinase-activated receptor peptide<br />
Line 153: Line 180:
**[[1ktr]] – mFab + oligohistidine peptide<br />
**[[1ktr]] – mFab + oligohistidine peptide<br />
**[[1p4b]] – mFab + GCN4 peptide<br />
**[[1p4b]] – mFab + GCN4 peptide<br />
-
**[[5mo3]], [[6bb4]] – mFab + tau peptide<br />
+
**[[5mo3]], [[6bb4]], [[6dc8]], [[6dc9]] – mFab + tau peptide<br />
**[[1zea]] – mFab anti-cholera toxin + peptide<br />
**[[1zea]] – mFab anti-cholera toxin + peptide<br />
**[[1sm3]] – mFab anti-breast tumor + peptide<br />
**[[1sm3]] – mFab anti-breast tumor + peptide<br />
Line 160: Line 187:
**[[4n8c]] – mFab + influenza peptide<br />
**[[4n8c]] – mFab + influenza peptide<br />
**[[4bh8]], [[4bh7]] – mFab anti-ARS murine germline + peptide<br />
**[[4bh8]], [[4bh7]] – mFab anti-ARS murine germline + peptide<br />
 +
**[[6sf6]] – mFab + COMP peptide<br />
 +
**[[6uud]], [[6x87]], [[6x8p]], [[6x8q]], [[6x8s]], [[6x8u]] – mFab + CSP peptide<br />
 +
**[[6lz4]] – raFab + MAP peptide<br />
*Anti-HIV Fab: peptide complex
*Anti-HIV Fab: peptide complex
Line 177: Line 207:
**[[2nyy]], [[2nz9]] – hFab + botulinum neurotoxin<br />
**[[2nyy]], [[2nz9]] – hFab + botulinum neurotoxin<br />
**[[3w2d]] – hFab + enterotoxin<br />
**[[3w2d]] – hFab + enterotoxin<br />
 +
**[[7ce2]] – hFab + tetanus toxin<br />
**[[4mxv]] – hFab anti-lymphotoxin-α + lymphotoxin-α<br />
**[[4mxv]] – hFab anti-lymphotoxin-α + lymphotoxin-α<br />
**[[2ybr]], [[2yc1]] – hFab + scorpion toxin<br />
**[[2ybr]], [[2yc1]] – hFab + scorpion toxin<br />
**[[2r4r]], [[2r4s]] – hFab + adrenergic receptor<br />
**[[2r4r]], [[2r4s]] – hFab + adrenergic receptor<br />
**[[4hj0]] – hFab + GIP receptor<br />
**[[4hj0]] – hFab + GIP receptor<br />
 +
**[[6wmw]] – hFab + GFRAL receptor<br />
**[[2vxq]] – hFab + pollen allergen<br />
**[[2vxq]] – hFab + pollen allergen<br />
**[[3nfp]], [[3iu3]] – hFab + interleukin-2 receptor<br />
**[[3nfp]], [[3iu3]] – hFab + interleukin-2 receptor<br />
Line 186: Line 218:
**[[1s78]] - hFab commercial + ERBB-2<br />
**[[1s78]] - hFab commercial + ERBB-2<br />
**[[3hmx]] - hFab commercial + IL-12<br />
**[[3hmx]] - hFab commercial + IL-12<br />
 +
**[[6wzm]] – hFab + IL-8<br />
 +
**[[6u6u]] - hFab + IL-36R<br />
**[[3eoa]], [[3eob]] - hFab commercial + integrin<br />
**[[3eoa]], [[3eob]] - hFab commercial + integrin<br />
 +
**[[6v4p]] - hFab + integrin – Cryo EM<br />
**[[1h0d]] – hFab 26-2F + angiogenin<br />
**[[1h0d]] – hFab 26-2F + angiogenin<br />
**[[1iqd]] – hFab BO2C11 + human factor VIII<br />
**[[1iqd]] – hFab BO2C11 + human factor VIII<br />
Line 194: Line 229:
**[[4k7p]] – hFab RHUMAB6 + mFab 10C4<br />
**[[4k7p]] – hFab RHUMAB6 + mFab 10C4<br />
**[[5xf1]], [[5xez]] – hFab + glucagon receptor<br />
**[[5xf1]], [[5xez]] – hFab + glucagon receptor<br />
 +
**[[4hj0]], [[6jbt]], [[6k0y]], [[7bxa]] – hFab + PD-1<br />
 +
**[[6wzj]], [[6wzk]], [[6wzl]] - hFab + chemokine<br />
 +
**[[6a3w]] - hFab + TNFR 9<br />
 +
**[[6rps]] - hFab + carbonic anhydrase<br />
 +
**[[6r2s]] – hFab + duffy receptor<br />
 +
**[[6al5]] - hFab anti-CD19 + CD19<br />
 +
**[[6vja]] – hFab + CD20 – Cryo EM<br />
 +
**[[6aod]] - hFab + coagulation factor XI<br />
 +
**[[6ss2]], [[6ss4]], [[6ss6]] - hFab + arginase<br />
 +
**[[6s5a]] – hFab + LALA<br />
 +
**[[6w7s]], [[6wh9]] – hFab + KR1<br />
 +
**[[6e63]], [[6rcu]], [[6rcv]], [[6wn1]] – hFab + CSP protein<br />
 +
**[[6mb3]], [[6mhg]] – hFab + CSP protein – Cryo EM<br />
 +
**[[6umx]] - hFab + growth factor 8<br />
 +
**[[6umg]] - hFab + CGRP receptor<br />
 +
**[[6bfq]], [[6bfs]] – hFab + GM-CSF<br />
 +
**[[6bit]] – hFab + SIRP-alpha<br />
 +
**[[6t9e]] - hFab + platelet factor B<br />
 +
**[[6t9d]] - hFab + VEGF<br />
*Human Fab: viral protein complex
*Human Fab: viral protein complex
Line 200: Line 254:
**[[6iw0]], [[6iw2]], [[6ivz]] – hFab + yellow fever E protein <br />
**[[6iw0]], [[6iw2]], [[6ivz]] – hFab + yellow fever E protein <br />
**[[3iyw]] – hFab mAb + West Nile virus surface protein<br />
**[[3iyw]] – hFab mAb + West Nile virus surface protein<br />
-
**[[4ubd]], [[5vag]] – hFab + influenza virus haemagglutinin<br />
+
**[[4ubd]], [[5vag]], [[6mlm]], [[6p3s]], [[6pdx]], [[6uig]] – hFab + influenza virus hemagglutinin<br />
-
**[[2ghw]] - hFab anti-SARS + SARS spike protein<br />
+
**[[6lxi]], [[6lxj]] – hFab + influenza virus neuraminidase<br />
 +
**[[2ghw]], [[6xe1]], [[6ym0]], [[7bz5]], [[7jx3]], [[7k8v]], [[7k8w]] - hFab anti-SARS + SARS spike protein<br />
 +
**[[7cac]], [[7cah]], [[7cai]], [[7cak]], [[7k8s]], [[7k8t]], [[7k8u]], [[7k8z]], [[7ls9]], [[7lss]] - hFab anti-SARS + SARS spike protein – Cryo EM<br />
 +
**[[7l0n]] - hFab anti-SARS + SARS spike protein + ACE<br />
 +
**[[7cr5]] - hFab anti-SARS + SARS nucleoprotein<br />
 +
**[[7dwt]], [[7dwu]] – hFab + Dengue envelope glycoprotein – Cryo EM<br />
 +
**[[6weq]], [[6wer]] – hFab + dengue virus NS1c <br />
 +
**[[6cmg]], [[6cmi]] – hFab + Hendra virus glycoprotein <br />
 +
**[[6bp2]] – hFab + Marburg virus glycoprotein <br />
 +
**[[6txz]] – hFab + Hepatitis A virus protein<br />
 +
**[[6ieb]], [[6iec]], [[6iek]] – hFab + Rift Valley fever virus protein<br />
 +
**[[6w09]] – hFab + Chikungunya glycoproteins – Cryo EM<br />
 +
**[[6w1c]] – hFab + Mayaro virus glycoproteins – Cryo EM<br />
 +
**[[6vyv]] – hFab + Ross River virus glycoproteins – Cryo EM<br />
 +
**[[6dfi]], [[6dfj]], [[6jep]], [[6jfh]], [[6jfi]], [[7bpk]] – hFab + zika protein <br />
 +
**[[6uoe]] – hFab + herpesvirus protein<br />
 +
**[[6pci]], [[6dzm]], [[6uye]] – hFab + ebola spike proteins – Cryo EM<br />
 +
**[[6oz9]] – hFab + ebola glycoprotein<br />
*Mouse Fab: protein complex
*Mouse Fab: protein complex
Line 226: Line 297:
**[[2nr6]], [[5vyf]] – mFab + allergen <br />
**[[2nr6]], [[5vyf]] – mFab + allergen <br />
**[[2hlf]], [[2ht2]], [[2ht3]], [[2ht4]], [[2htk]], [[2htl]], [[2h2p]], [[2h2s]], [[2exw]], [[2exy]], [[2fee]], [[1ots]] – mFab + exchange transporter ClCA<br />
**[[2hlf]], [[2ht2]], [[2ht3]], [[2ht4]], [[2htk]], [[2htl]], [[2h2p]], [[2h2s]], [[2exw]], [[2exy]], [[2fee]], [[1ots]] – mFab + exchange transporter ClCA<br />
 +
**[[7kgv]] – mFab + neutral amino acid transporter<br />
**[[2ez0]], [[2fec]], [[2fed]], [[1ott]], [[1otu]] - mFab + exchange transporter ClCA (mutant)<br />
**[[2ez0]], [[2fec]], [[2fed]], [[1ott]], [[1otu]] - mFab + exchange transporter ClCA (mutant)<br />
**[[1z3g]] – mFab 2A8 + ookinete surface protein<br />
**[[1z3g]] – mFab 2A8 + ookinete surface protein<br />
Line 243: Line 315:
**[[6a77]], [[6a78]] - mFab anti-ROBO1 + roundabout homolog<br />
**[[6a77]], [[6a78]] - mFab anti-ROBO1 + roundabout homolog<br />
**[[6a79]] - mFab anti-ROBO1 (mutant) + roundabout homolog<br />
**[[6a79]] - mFab anti-ROBO1 (mutant) + roundabout homolog<br />
 +
**[[7jti]] – mFab + retinol-binding protein<br />
 +
**[[6mlk]] – mFab + DEBS<br />
 +
**[[6cxy]], [[6vel]] – mFab + cadherin<br />
 +
**[[6hx4]] – mFab + antitrypsin<br />
 +
**[[6nex]] – mFab anti-cocaine + ighg<br />
 +
**[[7a65]], [[7a69]], [[7a6c]], [[7a6e]], [[7a6f]] – mFab + ABCB + drug – Cryo EM<br />
 +
**[[6ohg]] – mFab + P230<br />
*Mouse Fab: viral protein complex
*Mouse Fab: viral protein complex
Line 251: Line 330:
**[[2r29]], [[4l5f]] – mFab + Dengue envelope glycoprotein<br />
**[[2r29]], [[4l5f]] – mFab + Dengue envelope glycoprotein<br />
**[[3fmg]] - mFab 4F8 + Simian rotavirus glycoprotein VP7<br />
**[[3fmg]] - mFab 4F8 + Simian rotavirus glycoprotein VP7<br />
-
**[[3j1s]] – mFab A20 + adeno-associated virus capsid protein Vp1<br />
+
**[[3j1s]], [[6ewb]] – mFab + Vp1<br />
**[[2xqy]] - mFab anti-pseudorabies virus + glycoprotein H <br />
**[[2xqy]] - mFab anti-pseudorabies virus + glycoprotein H <br />
-
**[[3bgf]], [[4f2m]] – mFab + coronavirus spike protein<br />
+
**[[3bgf]], [[4f2m]] – mFab + SARS spike protein<br />
**[[3v7a]] - mFab + norovirus capsid protein<br />
**[[3v7a]] - mFab + norovirus capsid protein<br />
 +
**[[6l62]] - mFab + circovirus capsid protein – Cryo EM<br />
**[[2i9l]] – mFab + vaccinia virus protein<br />
**[[2i9l]] – mFab + vaccinia virus protein<br />
**[[4etq]] – mFab anti-vaccinia + IMV membrane protein<br />
**[[4etq]] – mFab anti-vaccinia + IMV membrane protein<br />
 +
**[[6j5d]] - mFab + louping ILL virus protein – cryo EM<br />
 +
**[[6j5g]], [[6j5f]] - mFab + tick-borne encephalitis virus protein <br />
 +
**[[6uvo]] – mFab + HRSV protein<br />
 +
**[[6cxc]] – mFab + HRSV protein – Cryo EM<br />
 +
**[[6tys]] – mFab + Nipah virus glycoprotein – Cryo EM<br />
 +
**[[7ebr]], [[7ebz]], [[7ec5]], [[7ecy]] – mFab + enterovirus glycoproteins – Cryo EM<br />
*Other Fab: protein complex
*Other Fab: protein complex
Line 266: Line 352:
**[[3uaj]], [[3uc0]] – Fab + envelope protein - chimpanzee<br />
**[[3uaj]], [[3uc0]] – Fab + envelope protein - chimpanzee<br />
**[[3b9k]] – rFab + CD8<br />
**[[3b9k]] – rFab + CD8<br />
 +
**[[6i9i]] – rFab + Rift Valley fever virus glycoprotein<br />
 +
**[[6t3f]] – rFab + Nipah virus glycoprotein<br />
 +
**[[6osh]], [[6osn]], [[6osv]] – rFab + ROR2<br />
 +
**[[6h5n]] – raFab + malaria protein<br />
 +
**[[6zvf]] – raFab + galectin<br />
 +
**[[6icc]], [[6icf]] – raFab + S2P<br />
 +
**[[7b09]] - vFab + hantavirus envelope polyprotein – vole - Cryo EM<br />
 +
**[[6tyb]] - rmFab + SIV gp160 + CD4 – rhesus monkey<br />
*Fab: protein ternary complex
*Fab: protein ternary complex
Line 272: Line 366:
**[[3j70]] – hFab + gp41 + gp120 + CD4<br />
**[[3j70]] – hFab + gp41 + gp120 + CD4<br />
**[[4mxw]] – hFab anti-lymphotoxin-α + lymphotoxin-α + lymphotoxin-β + TNFR 3<br />
**[[4mxw]] – hFab anti-lymphotoxin-α + lymphotoxin-α + lymphotoxin-β + TNFR 3<br />
-
**[[6mid]] – hFab + zika E protein + zika M protein<br />**[[3bsz]] – mFab + transthyretin + retinol-binding protein<br />
+
**[[6mid]] – hFab + zika E protein + zika M protein<br />
 +
**[[7cbp]], [[7kcr]] – hFab + zika E protein + zika M protein – Cryo EM<br />
 +
**[[6nha]] – hFab + beta microglobulin + IgG receptor<br />
 +
**[[7kpb]] – hFab + TNF + TNFR<br />
 +
**[[6b9z]] – hFab + protein L + immunoblobulin binding protein<br />
 +
**[[6b9y]], [[6bae]], [[6bah]] – hFab + protein L + meditope + immunoblobulin binding protein<br />
 +
**[[3bsz]] – mFab + transthyretin + retinol-binding protein<br />
**[[2zck]] - mFab 8G8F5 + PSA + reaction intermediate<br />
**[[2zck]] - mFab 8G8F5 + PSA + reaction intermediate<br />
**[[3rhw]], [[3ri5]], [[3ria]], [[3rif]] – mFab + glutamate-gated Cl- channel + drug<br />
**[[3rhw]], [[3ri5]], [[3ria]], [[3rif]] – mFab + glutamate-gated Cl- channel + drug<br />
Line 280: Line 380:
**[[2hmi]], [[1n5y]], [[1n6q]], [[1r0a]], [[1hys]] – mFab 28 + reverse transcriptase + DNA<br />
**[[2hmi]], [[1n5y]], [[1n6q]], [[1r0a]], [[1hys]] – mFab 28 + reverse transcriptase + DNA<br />
**[[3klh]] – mFab + P66 RT + P51 RT + DNA<br />
**[[3klh]] – mFab + P66 RT + P51 RT + DNA<br />
-
**[[3w11]], [[3w12]] , [[3w13]] , [[5kqv]], [[4oga]] – mFab + insulin + insulin receptor<br />
+
**[[3w11]], [[3w12]] , [[3w13]] , [[3w14]], [[4oga]], [[5kqv]] – mFab + insulin + insulin receptor<br />
**[[1t03]] - mFab + Pol polyprotein + DNA<br />
**[[1t03]] - mFab + Pol polyprotein + DNA<br />
**[[1xcq]], [[1xct]], [[1xf5]] - mFab + capsid C + protein L<br />
**[[1xcq]], [[1xct]], [[1xf5]] - mFab + capsid C + protein L<br />
Line 290: Line 390:
**[[1igy]] - hFab IgG1 <br />
**[[1igy]] - hFab IgG1 <br />
-
**[[1igt]] – mFab IGG2A <br />
+
**[[1igt]], [[6rnn]], [[6rux]] – mFab <br />
*Fc Fragments
*Fc Fragments
Line 339: Line 439:
* Single chain variable fragment (scFv)
* Single chain variable fragment (scFv)
-
**[[6ehy]], [[6ehx]], [[6ehw]], [[6ehv]], [[5j75]], [[5j74]], [[5c2b]], [[2a9n]], [[2a9m]] – hscFv<br />
+
**[[6ehy]], [[6ehx]], [[6ehw]], [[6ehv]], [[5j75]], [[5j74]], [[5c2b]], [[2a9n]], [[2a9m]], [[6tcs]] – hscFv<br />
 +
**[[6j9o]] – hscFv anti-influenza<br />
**[[5wn9]], [[4kv5]] – hscFv + peptide<br />
**[[5wn9]], [[4kv5]] – hscFv + peptide<br />
**[[1n4x]], [[1moe]], [[5vf2]], [[5i4f]], [[5b3n]], [[4nko]], [[4nkm]], [[4nkd]], [[4h0i]], [[4h0g]], [[4gqp]], [[3umt]], [[3nn8]] – mscFv<br />
**[[1n4x]], [[1moe]], [[5vf2]], [[5i4f]], [[5b3n]], [[4nko]], [[4nkm]], [[4nkd]], [[4h0i]], [[4h0g]], [[4gqp]], [[3umt]], [[3nn8]] – mscFv<br />
Line 352: Line 453:
**[[5jz7]] – hscFv + NGF<br />
**[[5jz7]] – hscFv + NGF<br />
**[[5jym]], [[5jyl]] – hscFv + cadherin<br />
**[[5jym]], [[5jyl]] – hscFv + cadherin<br />
 +
**[[7jum]] – hscFv + Pfs230<br />
 +
**[[6j71]] - hscFv + ERBB-2<br />
**[[5f3j]] – mscFv + Duffy receptor<br />
**[[5f3j]] – mscFv + Duffy receptor<br />
**[[6eqc]], [[5ogi]] – mscFv + hexon protein<br />
**[[6eqc]], [[5ogi]] – mscFv + hexon protein<br />

Revision as of 08:56, 19 April 2021

3D structures of Monoclonal Antibody

Updated on 19-April-2021

Humanized mouse antibody (hmFab) is a modified mFab which resembles more hFab.

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jaime Prilusky, Joel L. Sussman

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