1e93

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[[Image:1e93.gif|left|200px]]
[[Image:1e93.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1e93 |SIZE=350|CAPTION= <scene name='initialview01'>1e93</scene>, resolution 2.00&Aring;
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The line below this paragraph, containing "STRUCTURE_1e93", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=HEM:Hem+Binding+Site+For+Chain+A+HIS+A+54+Is+The+Distal+HIS+...'>HEM</scene>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OMT:S-DIOXYMETHIONINE'>OMT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= KATA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=584 Proteus mirabilis])
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-->
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|DOMAIN=
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{{STRUCTURE_1e93| PDB=1e93 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e93 OCA], [http://www.ebi.ac.uk/pdbsum/1e93 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1e93 RCSB]</span>
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}}
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'''HIGH RESOLUTION STRUCTURE AND BIOCHEMICAL PROPERTIES OF A RECOMBINANT CATALASE DEPLETED IN IRON'''
'''HIGH RESOLUTION STRUCTURE AND BIOCHEMICAL PROPERTIES OF A RECOMBINANT CATALASE DEPLETED IN IRON'''
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[[Category: Jouve, H M.]]
[[Category: Jouve, H M.]]
[[Category: Sainz, G.]]
[[Category: Sainz, G.]]
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[[Category: hem]]
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[[Category: Hem]]
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[[Category: hydrogen peroxide]]
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[[Category: Hydrogen peroxide]]
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[[Category: iron]]
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[[Category: Iron]]
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[[Category: nadp]]
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[[Category: Nadp]]
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[[Category: oxidoreductase (h2o2 acceptor)]]
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[[Category: Peroxidase]]
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[[Category: peroxidase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:49:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:57:44 2008''
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Revision as of 11:49, 2 May 2008

Template:STRUCTURE 1e93

HIGH RESOLUTION STRUCTURE AND BIOCHEMICAL PROPERTIES OF A RECOMBINANT CATALASE DEPLETED IN IRON


Overview

Various enzymes use semi-stable ferryl intermediates and free radicals during their catalytic cycle, amongst them haem catalases. Structures for two transient intermediates (compounds I and II) of the NADPH-dependent catalase from Proteus mirabilis (PMC) have been determined by time-resolved X-ray crystallography and single crystal microspectrophotometry. The results show the formation and transformation of the ferryl group in the haem, and the unexpected binding of an anion during this reaction at a site distant from the haem.

About this Structure

1E93 is a Single protein structure of sequence from Proteus mirabilis. Full crystallographic information is available from OCA.

Reference

Ferryl intermediates of catalase captured by time-resolved Weissenberg crystallography and UV-VIS spectroscopy., Gouet P, Jouve HM, Williams PA, Andersson I, Andreoletti P, Nussaume L, Hajdu J, Nat Struct Biol. 1996 Nov;3(11):951-6. PMID:8901874 Page seeded by OCA on Fri May 2 14:49:01 2008

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