Sandbox GGC17

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The disease that Keratin 4 causes is white sponge nenus. White sponge nevus is an autosomal dominant disease which is caused by amutation of a certain keratin genes. White sponge nevus is going to be a main componenet for a group of inherited diseases that are going to provide a white bilateral, keratinized apperance typically appearing on the buccal mucosa.
The disease that Keratin 4 causes is white sponge nenus. White sponge nevus is an autosomal dominant disease which is caused by amutation of a certain keratin genes. White sponge nevus is going to be a main componenet for a group of inherited diseases that are going to provide a white bilateral, keratinized apperance typically appearing on the buccal mucosa.
== Relevance ==
== Relevance ==
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The two way parallel beta-sheet is where the C-terminal strand of one monomer is being positioned and anti-parallel to the N-terminal strand of the main adjacent monomer and this arrangement is not seen so far in any of the homologous structures. This is the <scene name='87/874949/00rainbow_ribbon/1'>Keratin 4 protein</scene>.
== Structural highlights ==
== Structural highlights ==
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. This is the <scene name='87/874949/00rainbow_ribbon/1'>Keratin 4 protein</scene>. This is the <scene name='87/874949/00helix1_res/1'>Alpha helix residues zoomed in</scene>. This is the <scene name='87/874949/00helix1_res/2'>Alpha helix residues zoomed out</scene>
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. This is the <scene name='87/874949/00helix1_res/1'>Alpha helix residues zoomed in</scene>. This is the <scene name='87/874949/00helix1_res/2'>Alpha helix residues zoomed out</scene>
</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>

Revision as of 16:49, 26 April 2021

Keratin 4

Keratin 4 protein

Drag the structure with the mouse to rotate

References

  1. doi: https://dx.doi.org/10.1016/j.ijbiomac.201412048
  2. Moore PS, Hierholzer J, DeWitt W, Gouan K, Djore D, Lippeveld T, Plikaytis B, Broome CV. Respiratory viruses and mycoplasma as cofactors for epidemic group A meningococcal meningitis. JAMA. 1990 Sep 12;264(10):1271-5. PMID:2117679
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