User:Dustin Soe/Sandbox 1
From Proteopedia
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| - | =Lipoprotein Lipase coupled with GPIHBP1= | ||
| - | <StructureSection load='6ob0' size='350' side='right' caption='Lipoprotein Lipase PDB' scene='87/877513/Original_scene/1'> | ||
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==Introduction== | ==Introduction== | ||
| - | <scene name='87/877513/Original_scene/1'>Lipoprotein Lipase</scene>(LPL) is an important enzyme for the breakdown of triglycerides in the body (Figure 1).<ref name=”Arora”>PMID:31072929</ref> [[Image:Simple_mech.png|400 px|right|thumb|Figure 1: breakdown of a triglyceride into a diglyceride and creation of one free fatty acid by LPL]] A [https://en.wikipedia.org/wiki/Lipase lipase] is an enzyme that is capable of catalyzing the [https://en.wikipedia.org/wiki/Hydrolysis hydrolysis] of fats/lipids which are consumed through oils. It is encoded by the [https://www.genecards.org/cgi-bin/carddisp.pl?gene=LPL p22 region in chromosome 8]. Once synthesized, it is secreted into the interstitial space in several tissues. The main site of action for <scene name='87/877513/Original_scene/1'>LPL</scene> is in the [https://www.pnas.org/content/pnas/116/5/1480/F1.large.jpg capillary lumen] within muscle and adipose tissues.<ref name=”Birrane”>PMID:30559189</ref> The function of this lipase is to hydrolyze [https://en.wikipedia.org/wiki/Triglyceride triglycerides] of very-low-density lipoproteins ([https://qph.fs.quoracdn.net/main-qimg-8e874e647baeb69b00203c47165247e2 VLDL]) and to aid in the delivery of lipid nutrients to vital tissues.<ref name=”Birrane”/ | + | <scene name='87/877513/Original_scene/1'>Lipoprotein Lipase</scene>(LPL) is an important enzyme for the breakdown of triglycerides in the body (Figure 1).<ref name=”Arora”>PMID:31072929</ref> [[Image:Simple_mech.png|400 px|right|thumb|Figure 1: breakdown of a triglyceride into a diglyceride and creation of one free fatty acid by LPL]] A [https://en.wikipedia.org/wiki/Lipase lipase] is an enzyme that is capable of catalyzing the [https://en.wikipedia.org/wiki/Hydrolysis hydrolysis] of fats/lipids which are consumed through oils. It is encoded by the [https://www.genecards.org/cgi-bin/carddisp.pl?gene=LPL p22 region in chromosome 8]. Once synthesized, it is secreted into the interstitial space in several tissues. The main site of action for <scene name='87/877513/Original_scene/1'>LPL</scene> is in the [https://www.pnas.org/content/pnas/116/5/1480/F1.large.jpg capillary lumen] within muscle and adipose tissues.<ref name=”Birrane”>PMID:30559189</ref> The function of this lipase is to hydrolyze [https://en.wikipedia.org/wiki/Triglyceride triglycerides] of very-low-density lipoproteins ([https://qph.fs.quoracdn.net/main-qimg-8e874e647baeb69b00203c47165247e2 VLDL]) and to aid in the delivery of lipid nutrients to vital tissues.<ref name=”Birrane” /> |
Revision as of 02:04, 28 April 2021
Introduction
(LPL) is an important enzyme for the breakdown of triglycerides in the body (Figure 1).[1]
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