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Sandbox GGC6

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== Disease ==
== Disease ==
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NT-4, along with other growth factors including neurotrophin-3 (NT-3), brain-derived neurotrophic factor (BDNF), and nerve growth factor (NGF) have all shown to be essential for survival of neurons. <ref>PMID: 10631974, PMID: 16411893</ref> These growth factors have been associated with parts of the cerebrum including the frontal lobe and limbic system because of their involvement in neurological processes like behavior, learning, and memory. <ref>PMID: 16411893</ref>
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NT-4, along with other growth factors including neurotrophin-3 (NT-3), brain-derived neurotrophic factor (BDNF), and nerve growth factor (NGF) have all shown to be essential for survival of neurons. <ref>PMID: 10631974</ref>, <ref>16411893</ref> These growth factors have been associated with parts of the cerebrum including the frontal lobe and limbic system because of their involvement in neurological processes like behavior, learning, and memory. <ref>PMID: 16411893</ref>
== Relevance ==
== Relevance ==

Revision as of 14:45, 28 April 2021

Neurotrophin-4

Neurotrophin-4

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References

  1. Robinson RC, Radziejewski C, Spraggon G, Greenwald J, Kostura MR, Burtnick LD, Stuart DI, Choe S, Jones EY. The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site. Protein Sci. 1999 Dec;8(12):2589-97. PMID:10631974
  2. 16411893
  3. Chao MV, Rajagopal R, Lee FS. Neurotrophin signalling in health and disease. Clin Sci (Lond). 2006 Feb;110(2):167-73. doi: 10.1042/CS20050163. PMID:16411893 doi:http://dx.doi.org/10.1042/CS20050163
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