2b25
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='2b25' size='340' side='right'caption='[[2b25]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='2b25' size='340' side='right'caption='[[2b25]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2b25]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2b25]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B25 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B25 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b25 OCA], [https://pdbe.org/2b25 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b25 RCSB], [https://www.ebi.ac.uk/pdbsum/2b25 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b25 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/TR61B_HUMAN TR61B_HUMAN]] Methyltransferase that catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in various tRNAs in mitochondrion, including tRNA(Leu) (decephering codons UUA or UUG), tRNA(Lys) and tRNA(Ser) (decephering codons UCA, UCU, UCG or UCC).<ref>PMID:23097428</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 09:42, 5 May 2021
Human putative tRNA(1-methyladenosine)methyltransferase
| |||||||||||
Categories: Human | Large Structures | Arrowsmith, C | Bochkarev, A | Dong, A | Edwards, A | Loppnau, P | Plotnikov, A N | Structural genomic | Sundstrom, M | Tempel, W | Weigelt, J | Wu, H | Zeng, H | Methyl transferase | Sam | Sgc | Transferase
