6l8r
From Proteopedia
(Difference between revisions)
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==membrane-bound PD-L1-CD== | ==membrane-bound PD-L1-CD== | ||
| - | <StructureSection load='6l8r' size='340' side='right'caption='[[6l8r]]' scene=''> | + | <StructureSection load='6l8r' size='340' side='right'caption='[[6l8r]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full | + | <table><tr><td colspan='2'>[[6l8r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L8R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L8R FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l8r OCA], [https://pdbe.org/6l8r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l8r RCSB], [https://www.ebi.ac.uk/pdbsum/6l8r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l8r ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/PD1L1_HUMAN PD1L1_HUMAN]] Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.<ref>PMID:10581077</ref> <ref>PMID:11015443</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bin W]] | + | [[Category: Bin, W]] |
| - | [[Category: Bo O]] | + | [[Category: Bo, O]] |
| - | [[Category: Maorong W]] | + | [[Category: Cao, Y]] |
| + | [[Category: Maorong, W]] | ||
| + | [[Category: Cytoplasmic domain]] | ||
| + | [[Category: Immunosuppressant]] | ||
| + | [[Category: Membrane-bound]] | ||
| + | [[Category: Pd-l1]] | ||
| + | [[Category: Stability]] | ||
Revision as of 09:34, 12 May 2021
membrane-bound PD-L1-CD
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Categories: Human | Large Structures | Bin, W | Bo, O | Cao, Y | Maorong, W | Cytoplasmic domain | Immunosuppressant | Membrane-bound | Pd-l1 | Stability
