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2lll
From Proteopedia
(Difference between revisions)
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==Solution NMR structure of C-terminal globular domain of human Lamin-B2, Northeast Structural Genomics Consortium target HR8546A== | ==Solution NMR structure of C-terminal globular domain of human Lamin-B2, Northeast Structural Genomics Consortium target HR8546A== | ||
| - | <StructureSection load='2lll' size='340' side='right' caption='[[2lll]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2lll' size='340' side='right'caption='[[2lll]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lll]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2lll]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LLL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LLL FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LMNB2, LMN2 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LMNB2, LMN2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lll FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lll OCA], [https://pdbe.org/2lll PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lll RCSB], [https://www.ebi.ac.uk/pdbsum/2lll PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lll ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/LMNB2_HUMAN LMNB2_HUMAN]] Partial acquired lipodystrophy. The disease is caused by mutations affecting the gene represented in this entry. |
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/LMNB2_HUMAN LMNB2_HUMAN]] Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C]] | [[Category: Arrowsmith, C]] | ||
[[Category: CEBS, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes]] | [[Category: CEBS, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes]] | ||
Revision as of 10:13, 12 May 2021
Solution NMR structure of C-terminal globular domain of human Lamin-B2, Northeast Structural Genomics Consortium target HR8546A
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Categories: Human | Large Structures | Arrowsmith, C | CEBS, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes | Garcia, M | Houliston, S | Lemak, A | Min, J | Montelione, G T | Structural genomic | Xu, C | Yee, A | Ceb | Chaperone-enabled studies of epigenetic regulation enzyme | Immunoglobulin-like fold | Nesg | Psi-biology | Sgc | Structural protein
