2lm1
From Proteopedia
(Difference between revisions)
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==Solution NMR Structure of Lysine-specific demethylase lid from Drosophila melanogaster, Northeast Structural Genomics Consortium Target FR824D== | ==Solution NMR Structure of Lysine-specific demethylase lid from Drosophila melanogaster, Northeast Structural Genomics Consortium Target FR824D== | ||
| - | <StructureSection load='2lm1' size='340' side='right' caption='[[2lm1]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2lm1' size='340' side='right'caption='[[2lm1]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lm1]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2lm1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LM1 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CG9088, lid ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CG9088, lid ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lm1 OCA], [https://pdbe.org/2lm1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lm1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lm1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lm1 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/KDM5_DROME KDM5_DROME]] Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Specifically demethylates trimethylated H3 'Lys-4'. Required for the correct regulation of homeotic genes during development.<ref>PMID:11014813</ref> <ref>PMID:17311883</ref> <ref>PMID:17351631</ref> <ref>PMID:17351630</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Drome]] | [[Category: Drome]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Acton, T B]] | [[Category: Acton, T B]] | ||
[[Category: CEBS, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes]] | [[Category: CEBS, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes]] | ||
Revision as of 10:13, 12 May 2021
Solution NMR Structure of Lysine-specific demethylase lid from Drosophila melanogaster, Northeast Structural Genomics Consortium Target FR824D
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Categories: Drome | Large Structures | Acton, T B | CEBS, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes | Everett, J K | Kohan, E | Kusch, T | Lee, D | Mills, J L | Montelione, G T | Structural genomic | Sahdev, S | Szyperski, T | Xiao, R | Ceb | Chaperone-enabled studies of epigenetic regulation enzyme | Dna binding protein | PSI, Protein structure initiative | Psi-biology
