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1a6p
From Proteopedia
(Difference between revisions)
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<StructureSection load='1a6p' size='340' side='right'caption='[[1a6p]], [[Resolution|resolution]] 2.08Å' scene=''> | <StructureSection load='1a6p' size='340' side='right'caption='[[1a6p]], [[Resolution|resolution]] 2.08Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1a6p]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1a6p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A6P FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6p OCA], [https://pdbe.org/1a6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a6p RCSB], [https://www.ebi.ac.uk/pdbsum/1a6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a6p ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CD2_RAT CD2_RAT]] CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 10:36, 19 May 2021
ENGINEERING OF A MISFOLDED FORM OF CD2
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