1w8a

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<StructureSection load='1w8a' size='340' side='right'caption='[[1w8a]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1w8a' size='340' side='right'caption='[[1w8a]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1w8a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W8A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1w8a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W8A FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ozn|1ozn]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ozn|1ozn]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w8a OCA], [http://pdbe.org/1w8a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1w8a RCSB], [http://www.ebi.ac.uk/pdbsum/1w8a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1w8a ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w8a OCA], [https://pdbe.org/1w8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w8a RCSB], [https://www.ebi.ac.uk/pdbsum/1w8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w8a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SLIT_DROME SLIT_DROME]] A short-range repellent, controlling axon crossing of the midline and a long-range chemorepellent, controlling mesoderm migration and patterning away from the midline. May interact with extracellular matrix molecules. Repulsive ligand for the guidance receptor roundabout (robo) and prevents inappropriate midline crossing by Robo-expressing axons.<ref>PMID:2176636</ref> <ref>PMID:10102267</ref> <ref>PMID:3144436</ref> <ref>PMID:10102268</ref>
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[[https://www.uniprot.org/uniprot/SLIT_DROME SLIT_DROME]] A short-range repellent, controlling axon crossing of the midline and a long-range chemorepellent, controlling mesoderm migration and patterning away from the midline. May interact with extracellular matrix molecules. Repulsive ligand for the guidance receptor roundabout (robo) and prevents inappropriate midline crossing by Robo-expressing axons.<ref>PMID:2176636</ref> <ref>PMID:10102267</ref> <ref>PMID:3144436</ref> <ref>PMID:10102268</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 10:49, 19 May 2021

Third LRR domain of Drosophila Slit

PDB ID 1w8a

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