2m0y
From Proteopedia
(Difference between revisions)
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==Solution structure of the SH3 domain of DOCK180== | ==Solution structure of the SH3 domain of DOCK180== | ||
| - | <StructureSection load='2m0y' size='340' side='right' caption='[[2m0y]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2m0y' size='340' side='right'caption='[[2m0y]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2m0y]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2m0y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M0Y FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dock1 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dock1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0y OCA], [https://pdbe.org/2m0y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0y RCSB], [https://www.ebi.ac.uk/pdbsum/2m0y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0y ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/DOCK1_MOUSE DOCK1_MOUSE]] Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (By similarity). |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Dedicator of cytokinesis protein|Dedicator of cytokinesis protein]] | + | *[[Dedicator of cytokinesis protein 3D structures|Dedicator of cytokinesis protein 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Liu, X]] | [[Category: Liu, X]] | ||
[[Category: Wen, W]] | [[Category: Wen, W]] | ||
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
Revision as of 10:57, 19 May 2021
Solution structure of the SH3 domain of DOCK180
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