1ehv
From Proteopedia
| Line 1: | Line 1: | ||
[[Image:1ehv.gif|left|200px]] | [[Image:1ehv.gif|left|200px]] | ||
| - | + | <!-- | |
| - | + | The line below this paragraph, containing "STRUCTURE_1ehv", creates the "Structure Box" on the page. | |
| - | + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | |
| - | + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |
| - | | | + | or leave the SCENE parameter empty for the default display. |
| - | | | + | --> |
| - | + | {{STRUCTURE_1ehv| PDB=1ehv | SCENE= }} | |
| - | + | ||
| - | + | ||
| - | }} | + | |
'''A NEW CRYSTAL STRUCTURE FOR THE DODECAMER C-G-C-G-A-A-T-T-C-G-C-G: SYMMETRY EFFECTS ON SEQUENCE-DEPENDENT DNA STRUCTURE''' | '''A NEW CRYSTAL STRUCTURE FOR THE DODECAMER C-G-C-G-A-A-T-T-C-G-C-G: SYMMETRY EFFECTS ON SEQUENCE-DEPENDENT DNA STRUCTURE''' | ||
| Line 19: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | + | Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EHV OCA]. | |
==Reference== | ==Reference== | ||
A new crystal form for the dodecamer C-G-C-G-A-A-T-T-C-G-C-G: symmetry effects on sequence-dependent DNA structure., Johansson E, Parkinson G, Neidle S, J Mol Biol. 2000 Jul 14;300(3):551-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10884351 10884351] | A new crystal form for the dodecamer C-G-C-G-A-A-T-T-C-G-C-G: symmetry effects on sequence-dependent DNA structure., Johansson E, Parkinson G, Neidle S, J Mol Biol. 2000 Jul 14;300(3):551-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10884351 10884351] | ||
| - | [[Category: Protein complex]] | ||
[[Category: Johansson, E M.]] | [[Category: Johansson, E M.]] | ||
| - | [[Category: | + | [[Category: Crystal packing]] |
| - | [[Category: | + | [[Category: Dickerson dodecamer]] |
| - | [[Category: | + | [[Category: Dna]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 15:07:03 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 12:07, 2 May 2008
A NEW CRYSTAL STRUCTURE FOR THE DODECAMER C-G-C-G-A-A-T-T-C-G-C-G: SYMMETRY EFFECTS ON SEQUENCE-DEPENDENT DNA STRUCTURE
Overview
The dodecanucleotide d(CGCGAATTCGCG) has been crystallised in the space group P3(2)12, representing a new crystal form for this sequence. The structure has been solved by molecular replacement and refined at 1.8 A resolution. The present structure contrasts with previous ones for this sequence since it is situated on a crystallographic 2-fold axis, and the crystal symmetry reflects the palindromic nature of this sequence. Some features accord with previous observations, notably that the minor groove is hydrated with a continuous spine of solvent. There is no evidence of alkali metal ions within this spine. The minor groove retains its narrow width, although it is now symmetric and extends over the A/T tract. Various base and base-pair morphological parameters have been examined. Their values do not show significant correlations with earlier reports, suggesting that crystal packing effects on them are more dominant than has been hitherto realised.
About this Structure
Full crystallographic information is available from OCA.
Reference
A new crystal form for the dodecamer C-G-C-G-A-A-T-T-C-G-C-G: symmetry effects on sequence-dependent DNA structure., Johansson E, Parkinson G, Neidle S, J Mol Biol. 2000 Jul 14;300(3):551-61. PMID:10884351 Page seeded by OCA on Fri May 2 15:07:03 2008
