Caspase 3D structures
From Proteopedia
(Difference between revisions)
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**[[2h4w]], [[2h4y]], [[2h51]], [[2h54]], [[2hbr]], [[2hby]], [[2hbz]], [[2h48]], [[2fqq]], [[1rwk]], [[1rwm]], [[1rwn]], [[1rwo]], [[1rwp]], [[1rwv]], [[1rww]], [[1rwx]] - hCASP (mutant) + inhibitor<br /> | **[[2h4w]], [[2h4y]], [[2h51]], [[2h54]], [[2hbr]], [[2hby]], [[2hbz]], [[2h48]], [[2fqq]], [[1rwk]], [[1rwm]], [[1rwn]], [[1rwo]], [[1rwp]], [[1rwv]], [[1rww]], [[1rwx]] - hCASP (mutant) + inhibitor<br /> | ||
**[[1ice]] – hCASP + tetrapeptide aldehyde<br /> | **[[1ice]] – hCASP + tetrapeptide aldehyde<br /> | ||
| + | **[[6vie]] – hCASP + gasdermin<br /> | ||
**[[6kn0]] – hCASP (mutant) + gasdermin<br /> | **[[6kn0]] – hCASP (mutant) + gasdermin<br /> | ||
| + | **[[6pzp]] – hCASP + VX-765<br /> | ||
| + | **[[7keu]] – hCASP CARD domain + ASC CARD domain – Cryo-EM<br /> | ||
**[[1m72]] – SfCASP + polypeptide inhibitor<br /> | **[[1m72]] – SfCASP + polypeptide inhibitor<br /> | ||
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**[[2xzd]], [[2xzt]], [[2y0b]] - hCASP subunits P12, P17 + DARPIN-3.4<br /> | **[[2xzd]], [[2xzt]], [[2y0b]] - hCASP subunits P12, P17 + DARPIN-3.4<br /> | ||
**[[3pcx]], [[3pd1]], [[3pd0]], [[3gjq]], [[3gjr]], [[3gjs]], [[3gjt]], [[3edq]], [[3edr]], [[2cnk]], [[2cnl]], [[2cnn]], [[2cno]], [[2cdr]], [[2h65]], [[1cp3]], [[1pau]], [[4pry]] – hCASP + polypeptide inhibitor<br /> | **[[3pcx]], [[3pd1]], [[3pd0]], [[3gjq]], [[3gjr]], [[3gjs]], [[3gjt]], [[3edq]], [[3edr]], [[2cnk]], [[2cnl]], [[2cnn]], [[2cno]], [[2cdr]], [[2h65]], [[1cp3]], [[1pau]], [[4pry]] – hCASP + polypeptide inhibitor<br /> | ||
| - | **[[4dcj]], [[4dco]], [[4dcp]], [[4eha]], [[4ehd]], [[4ehf]], [[4ehh]], [[4ehk]], [[4ehl]], [[4ehn]], [[4ps0]], [[4ps1]] – hCASP subunits P12, P17 + polypeptide inhibitor<br /> | + | **[[4dcj]], [[4dco]], [[4dcp]], [[4eha]], [[4ehd]], [[4ehf]], [[4ehh]], [[4ehk]], [[4ehl]], [[4ehn]], [[4ps0]], [[4ps1]], [[6ckz]] – hCASP subunits P12, P17 + polypeptide inhibitor<br /> |
**[[2dko]], [[2cjx]], [[2cjy]], [[4qtx]], [[4qty]], [[4qu0]], [[4qu5]], [[4qu8]], [[4qu9]], [[4qua]], [[4qub]] [[4qud]], [[4que]], [[4qug]], [[4quh]], [[4qui]], [[4quj]], [[4qul]], [[5i9b]], [[5i9t]], [[5iab]], [[5iae]], [[5iag]], [[5iaj]], [[5iak]], [[5ian]], [[5iar]], [[5ias]], [[5ibc]], [[5ibp]], [[5ibr]], [[4qud]], [[6bfj]], [[6bfk]], [[6bfl]], [[6bfo]], [[6bg0]], [[6bg1]], [[6bg4]], [[6bgk]], [[6bgq]], [[6bgr]], [[6bgs]], [[6bh9]], [[6bha]], [[6bdv]] - hCASP (mutant) + polypeptide inhibitor<br /> | **[[2dko]], [[2cjx]], [[2cjy]], [[4qtx]], [[4qty]], [[4qu0]], [[4qu5]], [[4qu8]], [[4qu9]], [[4qua]], [[4qub]] [[4qud]], [[4que]], [[4qug]], [[4quh]], [[4qui]], [[4quj]], [[4qul]], [[5i9b]], [[5i9t]], [[5iab]], [[5iae]], [[5iag]], [[5iaj]], [[5iak]], [[5ian]], [[5iar]], [[5ias]], [[5ibc]], [[5ibp]], [[5ibr]], [[4qud]], [[6bfj]], [[6bfk]], [[6bfl]], [[6bfo]], [[6bg0]], [[6bg1]], [[6bg4]], [[6bgk]], [[6bgq]], [[6bgr]], [[6bgs]], [[6bh9]], [[6bha]], [[6bdv]] - hCASP (mutant) + polypeptide inhibitor<br /> | ||
**[[3kjf]], [[3h0e]], [[3deh]], [[3dei]], [[3dej]], [[3dek]], [[1re1]], [[1rhj]], [[1rhk]], [[1rhm]], [[1rhq]], [[1rhr]], [[1rhu]], [[1nme]], [[1nmq]], [[1nms]], [[1gfw]] – hCASP + inhibitor<br /> | **[[3kjf]], [[3h0e]], [[3deh]], [[3dei]], [[3dej]], [[3dek]], [[1re1]], [[1rhj]], [[1rhk]], [[1rhm]], [[1rhq]], [[1rhr]], [[1rhu]], [[1nme]], [[1nmq]], [[1nms]], [[1gfw]] – hCASP + inhibitor<br /> | ||
**[[3itn]], [[2j30]], [[2j31]], [[2j32]], [[2j33]], [[2c1e]], [[2c2k]], [[2c2m]], [[2c2o]], [[2c2z]], [[2h5i]], [[2h5j]], [[4jr0]] – hpro-CASP + polypeptide inhibitor<br /> | **[[3itn]], [[2j30]], [[2j31]], [[2j32]], [[2j33]], [[2c1e]], [[2c2k]], [[2c2m]], [[2c2o]], [[2c2z]], [[2h5i]], [[2h5j]], [[4jr0]] – hpro-CASP + polypeptide inhibitor<br /> | ||
[[4jqy]], [[4jqz]] - hpro-CASP (mutant)<br /> | [[4jqy]], [[4jqz]] - hpro-CASP (mutant)<br /> | ||
| - | **[[1i3o]] - hCASP (mutant) + XIAP-BIR2 | + | **[[1i3o]] - hCASP (mutant) + XIAP-BIR2<br /> |
| + | **[[6wi4]] – CASP + inhibitor – ''Porites asteroides''<br /> | ||
*CASP-4 | *CASP-4 | ||
| + | **[[6nry]] – hCASP <br /> | ||
**[[6kmz]] – hCASP (mutant) + gasdermin<br /> | **[[6kmz]] – hCASP (mutant) + gasdermin<br /> | ||
**[[6kmt]], [[6kmu]], [[6kn1]] – mCASP (mutant) - mouse<br /> | **[[6kmt]], [[6kmu]], [[6kn1]] – mCASP (mutant) - mouse<br /> | ||
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**[[1i4o]] - hCASP P20 subunit + XIAP<br /> | **[[1i4o]] - hCASP P20 subunit + XIAP<br /> | ||
**[[4jb8]], [[4lsz]] - hCASP large+small subunits + DARPIN<br /> | **[[4jb8]], [[4lsz]] - hCASP large+small subunits + DARPIN<br /> | ||
| - | **[[5ic6]], [[5ic4]], [[4zvo]], [[4zvp]], [[4zvq]], [[4zvr]], [[4zvs]], [[4zvt]], [[4zvu]], [[6cl2]], [[6cl1]], [[6cl0 | + | **[[5ic6]], [[5ic4]], [[4zvo]], [[4zvp]], [[4zvq]], [[4zvr]], [[4zvs]], [[4zvt]], [[4zvu]], [[6cl2]], [[6cl1]], [[6cl0]] - hCASP large+small subunits + peptide inhibitor<br /> |
*CASP-8 | *CASP-8 | ||
**[[5l08]] – hCASP – Cryo-EM<br /> | **[[5l08]] – hCASP – Cryo-EM<br /> | ||
| + | **[[6xkj]] – hCASP CARD domain 451-537 – Cryo-EM<br /> | ||
**[[4zbw]] - hCASP death effector domain<br /> | **[[4zbw]] - hCASP death effector domain<br /> | ||
**[[5h33]], [[5h31]] - hCASP death effector domain (mutant)<br /> | **[[5h33]], [[5h31]] - hCASP death effector domain (mutant)<br /> | ||
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**[[1nw9]] – hCASP catalytic domain + XIAP-BIR3<br /> | **[[1nw9]] – hCASP catalytic domain + XIAP-BIR3<br /> | ||
**[[3ygs]], [[4rhw]] – hpro-CASP + APAF-1 CARD | **[[3ygs]], [[4rhw]] – hpro-CASP + APAF-1 CARD | ||
| + | |||
| + | *CASP-11 | ||
| + | |||
| + | **[[6ns7]] – mCASP 60-243<br /> | ||
| + | **[[6kxg]] – mCASP CARD domain 1-463<br /> | ||
*''Drosophila melanogaster'' CASP | *''Drosophila melanogaster'' CASP | ||
Revision as of 08:48, 30 May 2021
3D structures of caspase
Updated on 30-May-2021
