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2mjn

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==Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1==
==Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1==
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<StructureSection load='2mjn' size='340' side='right' caption='[[2mjn]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='2mjn' size='340' side='right'caption='[[2mjn]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2mjn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MJN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2mjn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MJN FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TIA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TIA1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mjn OCA], [http://pdbe.org/2mjn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mjn RCSB], [http://www.ebi.ac.uk/pdbsum/2mjn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mjn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mjn OCA], [https://pdbe.org/2mjn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mjn RCSB], [https://www.ebi.ac.uk/pdbsum/2mjn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mjn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN]] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
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[[https://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN]] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Sattler, M]]
[[Category: Sattler, M]]
[[Category: Wang, I]]
[[Category: Wang, I]]

Revision as of 15:15, 2 June 2021

Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1

PDB ID 2mjn

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