2mx2
From Proteopedia
(Difference between revisions)
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==UBX-L domain of VCIP135== | ==UBX-L domain of VCIP135== | ||
| - | <StructureSection load='2mx2' size='340' side='right' caption='[[2mx2]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2mx2' size='340' side='right'caption='[[2mx2]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2mx2]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2mx2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MX2 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Vcpip1, Vcip135 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Vcpip1, Vcip135 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ubiquitinyl_hydrolase_1 Ubiquitinyl hydrolase 1], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.12 3.4.19.12] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mx2 OCA], [https://pdbe.org/2mx2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mx2 RCSB], [https://www.ebi.ac.uk/pdbsum/2mx2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mx2 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/VCIP1_RAT VCIP1_RAT]] Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP. Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.<ref>PMID:12473691</ref> <ref>PMID:15037600</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Buffalo rat]] | [[Category: Buffalo rat]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Ubiquitinyl hydrolase 1]] | [[Category: Ubiquitinyl hydrolase 1]] | ||
[[Category: Hrioaki, H]] | [[Category: Hrioaki, H]] | ||
Revision as of 15:22, 2 June 2021
UBX-L domain of VCIP135
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Categories: Buffalo rat | Large Structures | Ubiquitinyl hydrolase 1 | Hrioaki, H | Igarashi, R | Iwazu, T | Murayama, S | Shirakawa, M | Tochio, H | Golgi | Hydrolase | Mitosis | Ubx domain
