This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2n52

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==The solution structure of the kallikrein inhibitor SPINK6==
==The solution structure of the kallikrein inhibitor SPINK6==
-
<StructureSection load='2n52' size='340' side='right' caption='[[2n52]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='2n52' size='340' side='right'caption='[[2n52]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2n52]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N52 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2N52 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2n52]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N52 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N52 FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPINK6, UNQ844/PRO1782 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPINK6, UNQ844/PRO1782 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n52 OCA], [http://pdbe.org/2n52 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2n52 RCSB], [http://www.ebi.ac.uk/pdbsum/2n52 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2n52 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n52 OCA], [https://pdbe.org/2n52 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n52 RCSB], [https://www.ebi.ac.uk/pdbsum/2n52 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n52 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/ISK6_HUMAN ISK6_HUMAN]] Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8.<ref>PMID:20667819</ref> <ref>PMID:21439340</ref>
+
[[https://www.uniprot.org/uniprot/ISK6_HUMAN ISK6_HUMAN]] Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8.<ref>PMID:20667819</ref> <ref>PMID:21439340</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 23:
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
 +
[[Category: Large Structures]]
[[Category: Grotzinger, J]]
[[Category: Grotzinger, J]]
[[Category: Hydrolase inhibitor]]
[[Category: Hydrolase inhibitor]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]

Revision as of 15:39, 8 June 2021

The solution structure of the kallikrein inhibitor SPINK6

PDB ID 2n52

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2n52"
Personal tools