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2n5x
From Proteopedia
(Difference between revisions)
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==C-terminal domain of Cdc37 cochaperone== | ==C-terminal domain of Cdc37 cochaperone== | ||
| - | <StructureSection load='2n5x' size='340' side='right' caption='[[2n5x]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | + | <StructureSection load='2n5x' size='340' side='right'caption='[[2n5x]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2n5x]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2n5x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N5X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N5X FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1us7|1us7]], [[2w0g|2w0g]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1us7|1us7]], [[2w0g|2w0g]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDC37, CDC37A ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDC37, CDC37A ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n5x OCA], [https://pdbe.org/2n5x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n5x RCSB], [https://www.ebi.ac.uk/pdbsum/2n5x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n5x ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CDC37_HUMAN CDC37_HUMAN]] Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.<ref>PMID:8666233</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Dudhat, A]] | [[Category: Dudhat, A]] | ||
[[Category: Keramisanou, D]] | [[Category: Keramisanou, D]] | ||
Revision as of 15:40, 8 June 2021
C-terminal domain of Cdc37 cochaperone
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Categories: Human | Large Structures | Dudhat, A | Keramisanou, D | Pare, M | Cdc37 | Chaperone | Co-chaperone | Hsp90 | Kinase
