This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2nmm
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409== | ==Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409== | ||
| - | <StructureSection load='2nmm' size='340' side='right' caption='[[2nmm]], [[Resolution|resolution]] 2.70Å' scene=''> | + | <StructureSection load='2nmm' size='340' side='right'caption='[[2nmm]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2nmm]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2nmm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NMM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NMM FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PHPT1, PHP14 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PHPT1, PHP14 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nmm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nmm OCA], [https://pdbe.org/2nmm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nmm RCSB], [https://www.ebi.ac.uk/pdbsum/2nmm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nmm ProSAT], [https://www.topsan.org/Proteins/NESGC/2nmm TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/PHP14_HUMAN PHP14_HUMAN]] Exhibits phosphohistidine phosphatase activity. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nm/2nmm_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nm/2nmm_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 24: | Line 24: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Abashidze, M]] | [[Category: Abashidze, M]] | ||
[[Category: Acton, T]] | [[Category: Acton, T]] | ||
Revision as of 15:45, 8 June 2021
Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409
| |||||||||||
Categories: Human | Large Structures | Abashidze, M | Acton, T | Conover, K | Cunningham, K | Fang, Y | Forouhar, F | Hunt, J F | Kent, C | Kuzin, A P | Ma, L C | Montelione, G | Structural genomic | Seetharaman, J | Tong, L | Xiao, R | Hydrolase | Nesg q9h0y3 human phosphohistidine phosphatase | PSI, Protein structure initiative

