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2nrr
From Proteopedia
(Difference between revisions)
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==Crystal structure of the C-terminal RNAseH endonuclase domain of UvrC== | ==Crystal structure of the C-terminal RNAseH endonuclase domain of UvrC== | ||
| - | <StructureSection load='2nrr' size='340' side='right' caption='[[2nrr]], [[Resolution|resolution]] 1.20Å' scene=''> | + | <StructureSection load='2nrr' size='340' side='right'caption='[[2nrr]], [[Resolution|resolution]] 1.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2nrr]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2nrr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NRR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NRR FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ycz|1ycz]], [[1yd0|1yd0]], [[1yd1|1yd1]], [[1yd6|1yd6]], [[2nrt|2nrt]], [[2nrv|2nrv]], [[2nrw|2nrw]], [[2nrx|2nrx]], [[2nrz|2nrz]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ycz|1ycz]], [[1yd0|1yd0]], [[1yd1|1yd1]], [[1yd6|1yd6]], [[2nrt|2nrt]], [[2nrv|2nrv]], [[2nrw|2nrw]], [[2nrx|2nrx]], [[2nrz|2nrz]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">uvrC ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">uvrC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nrr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nrr OCA], [https://pdbe.org/2nrr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nrr RCSB], [https://www.ebi.ac.uk/pdbsum/2nrr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nrr ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/UVRC_THEMA UVRC_THEMA]] The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nr/2nrr_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nr/2nrr_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</div> | </div> | ||
<div class="pdbe-citations 2nrr" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2nrr" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[UvrABC|UvrABC]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Atcc 43589]] | [[Category: Atcc 43589]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Karakas, E]] | [[Category: Karakas, E]] | ||
[[Category: Kisker, C]] | [[Category: Kisker, C]] | ||
Revision as of 15:49, 8 June 2021
Crystal structure of the C-terminal RNAseH endonuclase domain of UvrC
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Categories: Atcc 43589 | Large Structures | Karakas, E | Kisker, C | Truglio, J J | Endonuclase | Hydrolase | Ner | Uvrc

