2nxn

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==T. thermophilus ribosomal protein L11 methyltransferase (PrmA) in complex with ribosomal protein L11==
==T. thermophilus ribosomal protein L11 methyltransferase (PrmA) in complex with ribosomal protein L11==
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<StructureSection load='2nxn' size='340' side='right' caption='[[2nxn]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='2nxn' size='340' side='right'caption='[[2nxn]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2nxn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NXN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NXN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2nxn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NXN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NXN FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ufk|1ufk]], [[2nxc|2nxc]], [[2nxe|2nxe]], [[2nxj|2nxj]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ufk|1ufk]], [[2nxc|2nxc]], [[2nxe|2nxe]], [[2nxj|2nxj]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">prmA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8]), rplK, rpl11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">prmA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8]), rplK, rpl11 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nxn OCA], [http://pdbe.org/2nxn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nxn RCSB], [http://www.ebi.ac.uk/pdbsum/2nxn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2nxn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nxn OCA], [https://pdbe.org/2nxn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nxn RCSB], [https://www.ebi.ac.uk/pdbsum/2nxn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nxn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PRMA_THET8 PRMA_THET8]] Methylates ribosomal protein L11; this reaction probably occurs before the protein is assembled into the ribosome. This function is dispensable for growth and thermostability. [[http://www.uniprot.org/uniprot/RL11_THETH RL11_THETH]] This protein binds directly to 23S ribosomal RNA (By similarity).
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[[https://www.uniprot.org/uniprot/PRMA_THET8 PRMA_THET8]] Methylates ribosomal protein L11; this reaction probably occurs before the protein is assembled into the ribosome. This function is dispensable for growth and thermostability. [[https://www.uniprot.org/uniprot/RL11_THETH RL11_THETH]] This protein binds directly to 23S ribosomal RNA (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nx/2nxn_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nx/2nxn_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2nxn" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2nxn" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ribosomal protein L11|Ribosomal protein L11]]
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*[[Ribosomal protein L11 methyltransferase|Ribosomal protein L11 methyltransferase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Thet8]]
[[Category: Thet8]]
[[Category: Dahlberg, A E]]
[[Category: Dahlberg, A E]]

Revision as of 15:53, 8 June 2021

T. thermophilus ribosomal protein L11 methyltransferase (PrmA) in complex with ribosomal protein L11

PDB ID 2nxn

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