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Core-binding factor

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Current revision (09:49, 10 June 2021) (edit) (undo)
 
Line 35: Line 35:
**[[6p59]] – hCBFb + elongin-B + elongin-C + virion infectivity factor<br />
**[[6p59]] – hCBFb + elongin-B + elongin-C + virion infectivity factor<br />
**[[6nil]] – hCBFb + A3F complex + virion infectivity factor – Cryo EM<br />
**[[6nil]] – hCBFb + A3F complex + virion infectivity factor – Cryo EM<br />
 +
**[[6vg2]], [[6vg8]], [[6vgd]], [[6vge]], [[6vgg]] – hCBFb + Runx2 + FLI1 + DNA<br />
**[[1ilf]] – mCBFb<br />
**[[1ilf]] – mCBFb<br />

Current revision

Human CBFα runt domain (magenta) complex with CBFβ heterodimerization domain (green) and DNA (PDB code 1h9d)

Drag the structure with the mouse to rotate

3D Structures of core-binding factor

Updated on 10-June-2021


References

  1. ↑ Bravo J, Li Z, Speck NA, Warren AJ. The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp. Nat Struct Biol. 2001 Apr;8(4):371-8. PMID:11276260 doi:http://dx.doi.org/10.1038/86264

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Alexander Berchansky

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