2pca

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Crystal structure of PH0725 from Pyrococcus horikoshii OT3==
==Crystal structure of PH0725 from Pyrococcus horikoshii OT3==
-
<StructureSection load='2pca' size='340' side='right' caption='[[2pca]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+
<StructureSection load='2pca' size='340' side='right'caption='[[2pca]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2pca]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'pyrococcus_shinkaii' 'pyrococcus shinkaii']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PCA FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2pca]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/'pyrococcus_shinkaii' 'pyrococcus shinkaii']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PCA FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dphB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 'Pyrococcus shinkaii'])</td></tr>
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dphB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 'Pyrococcus shinkaii'])</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diphthine_synthase Diphthine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.98 2.1.1.98] </span></td></tr>
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Diphthine_synthase Diphthine synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.98 2.1.1.98] </span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pca OCA], [http://pdbe.org/2pca PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pca RCSB], [http://www.ebi.ac.uk/pdbsum/2pca PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pca ProSAT], [http://www.topsan.org/Proteins/RSGI/2pca TOPSAN]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pca OCA], [https://pdbe.org/2pca PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pca RCSB], [https://www.ebi.ac.uk/pdbsum/2pca PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pca ProSAT], [https://www.topsan.org/Proteins/RSGI/2pca TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/DPHB_PYRHO DPHB_PYRHO]] S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.<ref>PMID:20873788</ref>
+
[[https://www.uniprot.org/uniprot/DPHB_PYRHO DPHB_PYRHO]] S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.<ref>PMID:20873788</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 24: Line 24:
==See Also==
==See Also==
*[[Diphthine synthase|Diphthine synthase]]
*[[Diphthine synthase|Diphthine synthase]]
-
*[[Ribonuclease|Ribonuclease]]
+
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
-
*[[Temp|Temp]]
+
== References ==
== References ==
<references/>
<references/>
Line 32: Line 31:
[[Category: Pyrococcus shinkaii]]
[[Category: Pyrococcus shinkaii]]
[[Category: Diphthine synthase]]
[[Category: Diphthine synthase]]
 +
[[Category: Large Structures]]
[[Category: Kunishima, N]]
[[Category: Kunishima, N]]
[[Category: Matsuura, Y]]
[[Category: Matsuura, Y]]

Revision as of 15:20, 17 June 2021

Crystal structure of PH0725 from Pyrococcus horikoshii OT3

PDB ID 2pca

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2pca"
Personal tools