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2pkk

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==Crystal structure of M tuberculosis Adenosine Kinase complexed with 2-fluro adenosine==
==Crystal structure of M tuberculosis Adenosine Kinase complexed with 2-fluro adenosine==
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<StructureSection load='2pkk' size='340' side='right' caption='[[2pkk]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
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<StructureSection load='2pkk' size='340' side='right'caption='[[2pkk]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2pkk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PKK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2pkk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PKK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2FA:2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL'>2FA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2FA:2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL'>2FA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rka|1rka]], [[1rkd|1rkd]], [[1bx4|1bx4]], [[2pkf|2pkf]], [[2pkm|2pkm]], [[2pkn|2pkn]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1rka|1rka]], [[1rkd|1rkd]], [[1bx4|1bx4]], [[2pkf|2pkf]], [[2pkm|2pkm]], [[2pkn|2pkn]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">adoK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">adoK ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pkk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pkk OCA], [http://pdbe.org/2pkk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pkk RCSB], [http://www.ebi.ac.uk/pdbsum/2pkk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pkk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pkk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pkk OCA], [https://pdbe.org/2pkk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pkk RCSB], [https://www.ebi.ac.uk/pdbsum/2pkk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pkk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ADOK_MYCTU ADOK_MYCTU]] ATP dependent phosphorylation of adenosine to monophosphate derivatives (By similarity).
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[[https://www.uniprot.org/uniprot/ADOK_MYCTU ADOK_MYCTU]] ATP dependent phosphorylation of adenosine to monophosphate derivatives (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Adenosine kinase|Adenosine kinase]]
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*[[Adenosine kinase 3D structures|Adenosine kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Adenosine kinase]]
[[Category: Adenosine kinase]]
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[[Category: Large Structures]]
[[Category: Owen, J L]]
[[Category: Owen, J L]]
[[Category: Palaninathan, S K]]
[[Category: Palaninathan, S K]]

Revision as of 15:26, 17 June 2021

Crystal structure of M tuberculosis Adenosine Kinase complexed with 2-fluro adenosine

PDB ID 2pkk

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