Cytochrome P450 3D structures

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**[[3ua1]] - hP4503A4 + ergocryptine<br />
**[[3ua1]] - hP4503A4 + ergocryptine<br />
**[[5vcg]] - hP4503A4 (mutant) + ergocryptine<br />
**[[5vcg]] - hP4503A4 (mutant) + ergocryptine<br />
-
**[[4ny4]], [[4d7d]], [[4d78]], [[4d75]], [[4d6z]], [[6bdm]], [[6bdk]], [[6bdi]], [[6bdh]], [[6bd8]], [[6bd7]], [[6bd6]], [[6bd5]], [[6bcz]], [[6ma8]], [[6ma7]], [[6ma6]], [[6dal]], [[6daj]], [[6dag]], [[6dac]], [[6dab]], [[6daa]], [[6da8]], [[6da5]], [[6da3]], [[6da2]], [[6une]], [[6ung]], [[6unh]], [[6uni]], [[6unj]], [[6unk]], [[6unl]], [[6unm]] - hP4503A4 + inhibitor <br />
+
**[[4ny4]], [[4d7d]], [[4d78]], [[4d75]], [[4d6z]], [[6bdm]], [[6bdk]], [[6bdi]], [[6bdh]], [[6bd8]], [[6bd7]], [[6bd6]], [[6bd5]], [[6bcz]], [[6ma8]], [[6ma7]], [[6ma6]], [[6dal]], [[6daj]], [[6dag]], [[6dac]], [[6dab]], [[6daa]], [[6da8]], [[6da5]], [[6da3]], [[6da2]], [[6une]], [[6ung]], [[6unh]], [[6uni]], [[6unj]], [[6unk]], [[6unl]], [[6unm]], [[7ks8]], [[7ksh]], [[7kvh]], [[7kvi]], [[7kvj]], [[7kvn]], [[7kvo]], [[7kvs]] - hP4503A4 + inhibitor <br />
**[[5te8]] - hP4503A4 + sedation drug <br />
**[[5te8]] - hP4503A4 + sedation drug <br />
**[[5a1p]], [[5a1r]] - hP4503A4 + progesterone <br />
**[[5a1p]], [[5a1r]] - hP4503A4 + progesterone <br />
 +
**[[7lxl]] - hP4503A4 + testosterone <br />
**[[6mjm]] - hP4503A5 <br />
**[[6mjm]] - hP4503A5 <br />
**[[5veu]] - hP4503A5 + inhibitor<br />
**[[5veu]] - hP4503A5 + inhibitor<br />
Line 98: Line 99:
* human P450 17 A1 family (steroid 17-α-hydroxylase 17,20 lyase)
* human P450 17 A1 family (steroid 17-α-hydroxylase 17,20 lyase)
-
**[[5uys]], [[3ruk]], [[6chi]], [[6cir]], [[6ciz]] - hP450 C17 + abiraterone derivative<br />
+
**[[5uys]], [[3ruk]], [[6chi]], [[6cir]], [[6ciz]], [[6wr0]], [[6ww0]] - hP450 C17 + abiraterone derivative<br />
-
**[[4nkv]] - hP450 C17 (mutant) + abiraterone derivative<br />
+
**[[4nkv]], [[6wr1]] - hP450 C17 (mutant) + abiraterone derivative<br />
**[[5irq]] - hP450 C17 + orteronel<br />
**[[5irq]] - hP450 C17 + orteronel<br />
**[[5irv]] - hP450 C17 + inhibitor<br />
**[[5irv]] - hP450 C17 + inhibitor<br />
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* P450cam or camphor-5 momooxygenase
* P450cam or camphor-5 momooxygenase
-
**[[1dz4]], [[1dz8]], [[1dz6]], [[1dz9]], [[5cp4]], [[1phc]], [[2cpp]], [[1yrc]], [[1yrd]], [[3l61]], [[3l62]], [[3l63]], [[3wrh]], [[3wri]], [[3wrk]] - PpP450cam - ''Pseudomona putida''<br />
+
**[[1dz4]], [[1dz8]], [[1dz6]], [[1dz9]], [[5cp4]], [[1phc]], [[2cpp]], [[1yrc]], [[1yrd]], [[3l61]], [[3l62]], [[3l63]], [[3wrh]], [[3wri]], [[3wrk]], [[6wpl]] - PpP450cam - ''Pseudomona putida''<br />
**[[2qbl]], [[2qbm]], [[2qbn]], [[2gqx]], [[2gr6]], [[2frz]], [[2h7s]], [[6cp4]], [[2cp4]], [[3cp4]], [[4cp4]], [[1c8j]], [[1geb]], [[2a1o]], [[3p6q]], [[3p6r]], [[3p6s]], [[3p6t]], [[3p6u]], [[3p6v]], [[3p6w]], [[3p6x]], [[4ek1]], [[5wk7]], [[6we6]], [[6wfl]] – PpP450cam (mutant) <br />
**[[2qbl]], [[2qbm]], [[2qbn]], [[2gqx]], [[2gr6]], [[2frz]], [[2h7s]], [[6cp4]], [[2cp4]], [[3cp4]], [[4cp4]], [[1c8j]], [[1geb]], [[2a1o]], [[3p6q]], [[3p6r]], [[3p6s]], [[3p6t]], [[3p6u]], [[3p6v]], [[3p6w]], [[3p6x]], [[4ek1]], [[5wk7]], [[6we6]], [[6wfl]] – PpP450cam (mutant) <br />
**[[2qbo]] - PpP450cam (mutant)+cyanide<br />
**[[2qbo]] - PpP450cam (mutant)+cyanide<br />
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**[[3p3l]], [[3p3o]], [[3p3x]], [[3p3z]] – P450 – ''Streptomyces thioluteus''<br />
**[[3p3l]], [[3p3o]], [[3p3x]], [[3p3z]] – P450 – ''Streptomyces thioluteus''<br />
**[[2rfb]] – PtP450 – ''Picrophilus torridus''<br />
**[[2rfb]] – PtP450 – ''Picrophilus torridus''<br />
-
**[[6gii]] – P450 – ''Tepidiphilus thermophilus''<br />
+
**[[6gii]], [[6laa]] – P450 – ''Tepidiphilus thermophilus''<br />
**[[1wiy]] – TtP450 – ''Thermus thermophilus''<br />
**[[1wiy]] – TtP450 – ''Thermus thermophilus''<br />
**[[4e2p]], [[5xw2]] - P450 – ''Streptococcus himastatinicus''<br />
**[[4e2p]], [[5xw2]] - P450 – ''Streptococcus himastatinicus''<br />
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**[[5ysm]] – AmP450 – ''Amycolatopsis mediterranei''<br />
**[[5ysm]] – AmP450 – ''Amycolatopsis mediterranei''<br />
**[[6f0c]], [[6f0b]] - P450 TXTC – ''Streptomyces acidiscabies''<br />
**[[6f0c]], [[6f0b]] - P450 TXTC – ''Streptomyces acidiscabies''<br />
-
**[[5gwe]] – CgP450 CREJ – ''Corynebacterium glutamicum''<br />
+
**[[5gwe]], [[7ccf]] – CgP450 CreJ – ''Corynebacterium glutamicum''<br />
**[[5y1i]] - P450 GFSF – ''Streptomyces graminofaciens''<br />
**[[5y1i]] - P450 GFSF – ''Streptomyces graminofaciens''<br />
**[[1cpt]] – PsP450 TERP - ''Pseudomonas sp.''<br />
**[[1cpt]] – PsP450 TERP - ''Pseudomonas sp.''<br />
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**[[3qi8]] – P450 – synthetic<br />
**[[3qi8]] – P450 – synthetic<br />
**[[6mi0]] – McP450 CYP51 – ''Methylcoccus capsulatus''<br />
**[[6mi0]] – McP450 CYP51 – ''Methylcoccus capsulatus''<br />
 +
**[[6ay4]], [[6ayb]], [[6ayc]] – P450 CYP51 + drug – ''Naegleria fowleri''<br />
**[[3dam]], [[3dan]], [[3dbm]] – P45074A2 – ''Parthenium argentatum''<br />
**[[3dam]], [[3dan]], [[3dbm]] – P45074A2 – ''Parthenium argentatum''<br />
**[[2rcm]], [[3cli]] - AtP45074A - ''Arabidopsis thaliana''<br />
**[[2rcm]], [[3cli]] - AtP45074A - ''Arabidopsis thaliana''<br />
Line 303: Line 305:
**[[3abb]] – SaP450 CYP105D6 - ''Streptomyces avermitilis''<br />
**[[3abb]] – SaP450 CYP105D6 - ''Streptomyces avermitilis''<br />
**[[3e5j]], [[3e5l]] - SaP450 CYP105P1 (mutant)<br />
**[[3e5j]], [[3e5l]] - SaP450 CYP105P1 (mutant)<br />
-
**[[2z3u]] - SsP450 CYP105A1 (mutant) – ''Streptomyces griseolus''<br />
+
**[[2z3u]] - SgP450 CYP105A1 (mutant) – ''Streptomyces griseolus''<br />
**[[5xnt]] - P450 CYP106A2 – ''Bacillus butanolivorans''<br />
**[[5xnt]] - P450 CYP106A2 – ''Bacillus butanolivorans''<br />
 +
**[[6l39]] - SrP450 CYP107G1 – ''Streptomyces rapamycinicus''<br />
**[[4wpz]] - SaP450 CYP107W1 <br />
**[[4wpz]] - SaP450 CYP107W1 <br />
**[[2whw]], [[2wi9]], [[2vz7]] – SvP450107L1 (mutant) – ''Streptomyces venezuelae''<br />
**[[2whw]], [[2wi9]], [[2vz7]] – SvP450107L1 (mutant) – ''Streptomyces venezuelae''<br />
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**[[6hqg]] - P450 CYP153 – ''Phenylobacterium zucineum''<br />
**[[6hqg]] - P450 CYP153 – ''Phenylobacterium zucineum''<br />
**[[6hqd]] – PsP450 CYP153 <br />
**[[6hqd]] – PsP450 CYP153 <br />
 +
**[[7ant]] – PoP450 CYP153 - ''Polaromonas''<br />
**[[1gwi]] - ScP450 CYP154C1<br />
**[[1gwi]] - ScP450 CYP154C1<br />
**[[6a7i]] - SvP450 CYP154C4 – ''Streptomyces violaceruber''<br />
**[[6a7i]] - SvP450 CYP154C4 – ''Streptomyces violaceruber''<br />
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**[[6gk5]] - ScP450 CYP267B1 <br />
**[[6gk5]] - ScP450 CYP267B1 <br />
**[[6g71]] - P450 CYP1232A24 - ''Arthrobacter''<br />
**[[6g71]] - P450 CYP1232A24 - ''Arthrobacter''<br />
 +
**[[6m4q]] - SspP450 – ''Streptomyces spectabilis''<br />
 +
**[[6j82]] - SbP450 TleB – ''Streptomyces blastmyceticus''<br />
 +
**[[6kbh]] – ReP450 – ''Rhodococcus erythropolis''<br />
*Other CYPs complexes
*Other CYPs complexes
**[[2rfc]] – PtP450+phenylimidazole<br />
**[[2rfc]] – PtP450+phenylimidazole<br />
-
**[[3wec]] – P450 + dihydroxy-aurachin Re – ''Rhodococcus erythropolis''<br />
+
**[[3wec]] – ReP450 + dihydroxy-aurachin Re <br />
**[[5ysw]] – AmP450+ rifamycin <br />
**[[5ysw]] – AmP450+ rifamycin <br />
**[[5omu]] – AmP450+ syringol <br />
**[[5omu]] – AmP450+ syringol <br />
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**[[3cv9]], [[2zbz]] - SgP450 CYP105A1 (mutant)+vitamin D3<br />
**[[3cv9]], [[2zbz]] - SgP450 CYP105A1 (mutant)+vitamin D3<br />
**[[2zbx]] - SgP450 CYP105A1+imidazole<br />
**[[2zbx]] - SgP450 CYP105A1+imidazole<br />
-
**[[5x7e]] - SsP450 CYP105A1 (mutant)+vitamin D2<br /
+
**[[5x7e]] - SgP450 CYP105A1 (mutant)+vitamin D2<br /
**[[3aba]] – SaP450 CYP105P1+filipin I <br />
**[[3aba]] – SaP450 CYP105P1+filipin I <br />
**[[3e5k]] - SaP450 CYP105P1 (mutant)+4-phenylimidazole<br />
**[[3e5k]] - SaP450 CYP105P1 (mutant)+4-phenylimidazole<br />
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**[[1eup]] – SeP450 CYP107A1+androstendione<br />
**[[1eup]] – SeP450 CYP107A1+androstendione<br />
**[[1egy]] - SeP450 CYP107A1+aminophenanthrene<br />
**[[1egy]] - SeP450 CYP107A1+aminophenanthrene<br />
 +
**[[6kzs]] - SgP450 CYP107F1 + imidazole<br />
 +
**[[6l3a]] - SrP450 CYP107G1 + drug<br />
**[[4wq0]] - SaP450 CYP107W1 + oligomycin<br />
**[[4wq0]] - SaP450 CYP107W1 + oligomycin<br />
**[[2vzm]] – SvP450 CYP107L1 (mutant)+narbomycin<br />
**[[2vzm]] – SvP450 CYP107L1 (mutant)+narbomycin<br />
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**[[5yhj]] - P450 CYP152N1 + myristic acid - ''Exiguobacterium''<br />
**[[5yhj]] - P450 CYP152N1 + myristic acid - ''Exiguobacterium''<br />
**[[5fyg]] - MhP450 CYP153A + dodecanoic acid<br />
**[[5fyg]] - MhP450 CYP153A + dodecanoic acid<br />
 +
**[[7ao7]] – PoP450 CYP153 + octanol <br />
 +
**[[6to2]] - NfP450 CYP154C4 + androstan derivative – ''Nocardia farcinica'' <br />
 +
**[[4j6b]], [[4jbc]], [[4jbd]], [[4jbt]] - NfP450 CYP154C5 + hormone<br />
**[[6a7j]] - SvP450 CYP154C4 + testosterone <br />
**[[6a7j]] - SvP450 CYP154C4 + testosterone <br />
**[[3r9c]] – MsP450 CYP164A2 + econazole<br />
**[[3r9c]] – MsP450 CYP164A2 + econazole<br />
-
**[[4do1]], [[4egm]], [[6c3j]], [[6c3h]], [[6c2d]], [[5yqh]], [[5yqa]], [[5uvb]], [[5u6w]], [[5u6u]], [[5u6t]], [[5kt1]], [[5kdb]], [[6oow]], [[6pq6]], [[6pqd]], [[6pqs]], [[6pqw]], [[6prr]], [[6prs]], [[6u30]], [[6u3k]] – RpP450 CYP199A4 + benzoate derivative<br />
+
**[[4do1]], [[4egm]], [[6c3j]], [[6c3h]], [[6c2d]], [[5yqh]], [[5yqa]], [[5uvb]], [[5u6w]], [[5u6u]], [[5u6t]], [[5kt1]], [[5kdb]], [[6oow]], [[6pq6]], [[6pqd]], [[6pqs]], [[6pqw]], [[6prr]], [[6prs]], [[6u30]], [[6u31]], [[6u3k]] – RpP450 CYP199A4 + benzoate derivative<br />
**[[5kdz]], [[5kdy]], [[6oox]] – RpP450 CYP199A4 (mutant) + benzoate derivative<br />
**[[5kdz]], [[5kdy]], [[6oox]] – RpP450 CYP199A4 (mutant) + benzoate derivative<br />
**[[4egn]] – RpP450 CYP199A4 + veratric acid<br />
**[[4egn]] – RpP450 CYP199A4 + veratric acid<br />
**[[4egp]] – RpP450 CYP199A4 + naphthoic acid<br />
**[[4egp]] – RpP450 CYP199A4 + naphthoic acid<br />
 +
**[[46unn]] – RpP450 CYP199A4 + cinnamic acid derivative<br />
**[[4ego]] – RpP450 CYP199A4 + indole derivative<br />
**[[4ego]] – RpP450 CYP199A4 + indole derivative<br />
**[[3a1l]] – StrP450 CYP245A1+dichlorochrompyrrolic acid <br />
**[[3a1l]] – StrP450 CYP245A1+dichlorochrompyrrolic acid <br />
Line 402: Line 415:
**[[4r20]] - zP450 17A2 + abiraterone – zebra fish<br />
**[[4r20]] - zP450 17A2 + abiraterone – zebra fish<br />
**[[6b82]] - zP450 17A1 (mutant) + abiraterone <br />
**[[6b82]] - zP450 17A1 (mutant) + abiraterone <br />
 +
**[[6m4p]] - SspP450 + antibiotic <br />
 +
**[[6zi3]] - P450 + rhamnose – ''Streptomyces antibioticus''<br />
 +
**[[6j84]] - SbP450 TleB + hydroxyl analog<br />
 +
**[[6j83]] - SbP450 TleB + NMVT<br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:28, 22 June 2021

3D Structures of Cytochrome P450

Updated on 22-June-2021

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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