This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2qds

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Crystal Structure of the Zinc Carbapenemase CPHA in Complex with the Inhibitor D-Captopril==
==Crystal Structure of the Zinc Carbapenemase CPHA in Complex with the Inhibitor D-Captopril==
-
<StructureSection load='2qds' size='340' side='right' caption='[[2qds]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
+
<StructureSection load='2qds' size='340' side='right'caption='[[2qds]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2qds]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aeromonas_liquefaciens"_kluyver_and_van_niel_1936 "aeromonas liquefaciens" kluyver and van niel 1936]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QDS FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2qds]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"aeromonas_liquefaciens"_kluyver_and_van_niel_1936 "aeromonas liquefaciens" kluyver and van niel 1936]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QDS FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MCO:1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC+ACID'>MCO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MCO:1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC+ACID'>MCO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x8g|1x8g]], [[1x8i|1x8i]], [[2gkl|2gkl]]</td></tr>
+
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1x8g|1x8g]], [[1x8i|1x8i]], [[2gkl|2gkl]]</div></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cphA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=644 "Aeromonas liquefaciens" Kluyver and van Niel 1936])</td></tr>
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cphA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=644 "Aeromonas liquefaciens" Kluyver and van Niel 1936])</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qds FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qds OCA], [http://pdbe.org/2qds PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qds RCSB], [http://www.ebi.ac.uk/pdbsum/2qds PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qds ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qds FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qds OCA], [https://pdbe.org/2qds PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qds RCSB], [https://www.ebi.ac.uk/pdbsum/2qds PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qds ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/BLAB_AERHY BLAB_AERHY]] Can hydrolyze carbapenem compounds.
+
[[https://www.uniprot.org/uniprot/BLAB_AERHY BLAB_AERHY]] Can hydrolyze carbapenem compounds.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 33: Line 33:
==See Also==
==See Also==
-
*[[Beta-lactamase|Beta-lactamase]]
+
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
-
*[[Tyrosine phosphatase|Tyrosine phosphatase]]
+
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 41: Line 41:
[[Category: Aeromonas liquefaciens kluyver and van niel 1936]]
[[Category: Aeromonas liquefaciens kluyver and van niel 1936]]
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
 +
[[Category: Large Structures]]
[[Category: Dideberg, O]]
[[Category: Dideberg, O]]
[[Category: Garau, G]]
[[Category: Garau, G]]

Revision as of 08:16, 25 June 2021

Crystal Structure of the Zinc Carbapenemase CPHA in Complex with the Inhibitor D-Captopril

PDB ID 2qds

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2qds"
Personal tools