2qs9
From Proteopedia
(Difference between revisions)
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==Crystal structure of the human retinoblastoma-binding protein 9 (RBBP-9). NESG target HR2978== | ==Crystal structure of the human retinoblastoma-binding protein 9 (RBBP-9). NESG target HR2978== | ||
| - | <StructureSection load='2qs9' size='340' side='right' caption='[[2qs9]], [[Resolution|resolution]] 1.72Å' scene=''> | + | <StructureSection load='2qs9' size='340' side='right'caption='[[2qs9]], [[Resolution|resolution]] 1.72Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2qs9]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2qs9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QS9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QS9 FirstGlance]. <br> |
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBBP9, BOG, RBBP10 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBBP9, BOG, RBBP10 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qs9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qs9 OCA], [https://pdbe.org/2qs9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qs9 RCSB], [https://www.ebi.ac.uk/pdbsum/2qs9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qs9 ProSAT], [https://www.topsan.org/Proteins/NESGC/2qs9 TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/RBBP9_HUMAN RBBP9_HUMAN]] May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Retinoblastoma-binding protein|Retinoblastoma-binding protein]] | + | *[[Retinoblastoma-binding protein 3D structures|Retinoblastoma-binding protein 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Acton, T B]] | [[Category: Acton, T B]] | ||
[[Category: Chen, C X]] | [[Category: Chen, C X]] | ||
Revision as of 08:31, 25 June 2021
Crystal structure of the human retinoblastoma-binding protein 9 (RBBP-9). NESG target HR2978
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Categories: Human | Large Structures | Acton, T B | Chen, C X | Cunningham, K | Hunt, J F | Kuzin, A | Maglaqui, M | Montelione, G T | Structural genomic | Owens, L | Seetharaman, J | Su, M | Tong, L | Vorobiev, S M | Xiao, R | Alternative splicing | B5t overexpressed gene protein | Bog | Cytoplasm | Hr2978 | Nesg | Nucleus | Phosphorylation | PSI, Protein structure initiative | Rbbp10 | Rbbp9 | Retinoblastoma-binding protein 10 | Retinoblastoma-binding protein 9 | Structural protein
