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DNA glycosylase 3D structures

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Line 14: Line 14:
*Adenine DG complex
*Adenine DG complex
 +
**[[7ef8]], [[7ef9]] – mADG + DNA with oxo-guanine - mouse<br />
 +
**[[7efa]] – mADG C-terminal + PCNA<br />
**[[1wei]], [[1mud]] - EcADG catalytic domain (mutant) + adenine<br />
**[[1wei]], [[1mud]] - EcADG catalytic domain (mutant) + adenine<br />
-
**[[6q0c]], [[6u7t]] – GsADG + DNA – ''Geobacillus stearothermophilus''<BR />
+
**[[6q0c]], [[6u7t]] - GsADG + DNA – ''Geobacillus stearothermophilus''<br />
 +
**[[6q0c]], [[6u7t]] – GsADG + DNA <BR />
**[[3g0q]], [[1vrl]], [[1rrq]], [[1rrs]], [[5kn8]] - GsADG (mutant) + DNA <BR />
**[[3g0q]], [[1vrl]], [[1rrq]], [[1rrs]], [[5kn8]] - GsADG (mutant) + DNA <BR />
**[[6u7t]], [[5kn9]] – GsADG + DNA with oxo-guanine<br />
**[[6u7t]], [[5kn9]] – GsADG + DNA with oxo-guanine<br />
Line 25: Line 28:
*Uracil DG
*Uracil DG
 +
**[[1akz]], [[3tkb]], [[1yuo]] - hUDG (mutant) <BR />
 +
**[[1okb]] – AcUDG catalytic domain – Atlantic cod<br />
**[[3a7n]], [[4wpk]], [[4wrw]], [[4wrx]] – MtUDG – ''Mycobacterium tuberculosis''<BR />
**[[3a7n]], [[4wpk]], [[4wrw]], [[4wrx]] – MtUDG – ''Mycobacterium tuberculosis''<BR />
-
**[[6ajs]] – MsUDG – ''Mycobacterium smegmatis''<br />
+
**[[6ail]], [[6ajs]], [[6io9]] – MsUDG X – ''Mycobacterium smegmatis''<br />
-
**[[6ajq]] – MsUDG (mutant)<br />
+
**[[6ajq]], [[6l5a]], [[6l5b]] – MsUDG X (mutant)<br />
-
**[[6ail]] – MsUDG X<br />
+
**[[3tr7]] – UDG – ''Coxiella burnetii''<br />
**[[3tr7]] – UDG – ''Coxiella burnetii''<br />
-
**[[1akz]], [[3tkb]], [[1yuo]] - hUDG (mutant) <BR />
 
**[[2jhq]] – UDG – ''Vibrio cholerae''<BR />
**[[2jhq]] – UDG – ''Vibrio cholerae''<BR />
**[[2owq]], [[3nt7]], [[4dof]], [[4dog]], [[4rib]], [[4lzb]], [[4qc9]], [[4qca]], [[5jx0]] – UDG (mutant) – Vaccinia virus<BR />
**[[2owq]], [[3nt7]], [[4dof]], [[4dog]], [[4rib]], [[4lzb]], [[4qc9]], [[4qca]], [[5jx0]] – UDG (mutant) – Vaccinia virus<BR />
Line 41: Line 44:
**[[2c2q]] – DrUDG (mutant) <BR />
**[[2c2q]] – DrUDG (mutant) <BR />
**[[1vk2]], [[1l9g]] – TmUDG - ''Thermotoga maritima''<BR />
**[[1vk2]], [[1l9g]] – TmUDG - ''Thermotoga maritima''<BR />
-
**[[1okb]] – AcUDG catalytic domain – Atlantic cod<br />
 
**[[3wdf]] – SaUDG - ''Staphylococcus aureus''<br />
**[[3wdf]] – SaUDG - ''Staphylococcus aureus''<br />
**[[3zor]] – BsUDG – ''Bacillus subtilis''<br />
**[[3zor]] – BsUDG – ''Bacillus subtilis''<br />
Line 50: Line 52:
*Uracil-DNA glycosylase complex with inhibitor protein
*Uracil-DNA glycosylase complex with inhibitor protein
-
**[[1udi]] – HsvUDG + UDG inhibitor protein<br />
 
**[[1ugh]] – hUDG + UDG inhibitor protein<br />
**[[1ugh]] – hUDG + UDG inhibitor protein<br />
**[[1uug]], [[1eui]], [[1lqg]], [[1lqm]] – EcUDG + UDG inhibitor protein <br />
**[[1uug]], [[1eui]], [[1lqg]], [[1lqm]] – EcUDG + UDG inhibitor protein <br />
Line 59: Line 60:
**[[4lyl]] – acUDG catalytic domain + UDG inhibitor protein <br />
**[[4lyl]] – acUDG catalytic domain + UDG inhibitor protein <br />
**[[4l5n]] – HsvUDG + PZA inhibitor protein <br />
**[[4l5n]] – HsvUDG + PZA inhibitor protein <br />
 +
**[[1udi]] – HsvUDG + UDG inhibitor protein<br />
*Uracil-DNA glycosylase complex with DNA
*Uracil-DNA glycosylase complex with DNA
-
**[[1lau]] – HsvUDG + DNA <br />
 
**[[4skn]] – hUDG (mutant) + DNA<br />
**[[4skn]] – hUDG (mutant) + DNA<br />
**[[2oxm]] – hUDG + DNA<br />
**[[2oxm]] – hUDG + DNA<br />
-
**[[4uqm]] – DrUDG + DNA<br />
 
**[[1ssp]], [[1q3f]] – hUDG + DNA + uracil<br />
**[[1ssp]], [[1q3f]] – hUDG + DNA + uracil<br />
**[[1emh]] – hUDG + DNA + deoxy pseudo-UMP<br />
**[[1emh]] – hUDG + DNA + deoxy pseudo-UMP<br />
Line 74: Line 74:
**[[2ddg]], [[2dem]], [[2dp6]] – TtUDG + DNA + deoxyphosphono ribose<br />
**[[2ddg]], [[2dem]], [[2dp6]] – TtUDG + DNA + deoxyphosphono ribose<br />
**[[5nnu]] – HhvUDG + DNA <br />
**[[5nnu]] – HhvUDG + DNA <br />
-
**[[6ajo]] – MsUDG + DNA<br />
+
**[[1lau]] – HsvUDG + DNA <br />
 +
**[[6ajo]], [[6iod]] – MsUDG X + DNA<br />
 +
**[[6l6s]] – MsUDG X (mutant) + DNA<br />
 +
**[[4uqm]] – DrUDG + DNA<br />
*Uracil-DNA glycosylase complex with uracil derivatives
*Uracil-DNA glycosylase complex with uracil derivatives
Line 84: Line 87:
**[[4wpl]], [[4wru]], [[4wrv]] – MtUDG + uracil<br />
**[[4wpl]], [[4wru]], [[4wrv]] – MtUDG + uracil<br />
**[[4wry]], [[4wrz]], [[4ws0]], [[4ws1]], [[4ws2]], [[4ws3]], [[4ws4]], [[4ws5]], [[4ws6]], [[4ws7]], [[4ws8]] – MtUDG + uracil derivative<br />
**[[4wry]], [[4wrz]], [[4ws0]], [[4ws1]], [[4ws2]], [[4ws3]], [[4ws4]], [[4ws5]], [[4ws6]], [[4ws7]], [[4ws8]] – MtUDG + uracil derivative<br />
-
**[[6ajr]] – MsUDG + uracil<br />
+
**[[6ajr]], [[6ioa]] – MsUDG X + uracil<br />
-
**[[6ajp]] – MsUDG + deoxy-UMP <br />
+
**[[6iob]], [[6ioc]] – MsUDG X (mutant) + uracil<br />
 +
**[[6ajp]] – MsUDG X + deoxy-UMP <br />
**[[2d3y]] – TtUDG + Fe4S4 + deoxy-UMP <br />
**[[2d3y]] – TtUDG + Fe4S4 + deoxy-UMP <br />
**[[2c53]] – HhvUDG (mutant) + deoxyuridine<br />
**[[2c53]] – HhvUDG (mutant) + deoxyuridine<br />
Line 92: Line 96:
*Uracil-DNA glycosylase other complexes
*Uracil-DNA glycosylase other complexes
-
**[[2hxm]], [[3fcf]], [[3fci]], [[3fck]], [[3fcl]] – hUDG + inhibitor<br />
+
**[[2hxm]], [[3fcf]], [[3fci]], [[3fck]], [[3fcl]], [[6vba]] – hUDG + inhibitor<br />
**[[5jk7]] – hUDG + DNA damage-binding protein + VPRBP + VPR <br />
**[[5jk7]] – hUDG + DNA damage-binding protein + VPRBP + VPR <br />
**[[5ayr]], [[5ays]] – hUDG + protein<br />
**[[5ayr]], [[5ays]] – hUDG + protein<br />
Line 128: Line 132:
**[[1ko9]], [[5an4]] – hOgg1<BR />
**[[1ko9]], [[5an4]] – hOgg1<BR />
-
**[[2xhi]], [[3ktu]], [[1hu0]], [[1fn7]] - hOgg1 + DNA<BR />
+
**[[2xhi]], [[3ktu]], [[1hu0]], [[1fn7]], [[6w0m]], [[6w0r]], [[6w13]] - hOgg1 + DNA<BR />
-
**[[1lwv]], [[1lww]], [[1lwy]] - hOgg1 + DNA<BR /> + guanine derivative<BR />
+
**[[2nob]], [[2noe]], [[2nof]], [[2noh]], [[2noi]], [[2nol]], [[2noz]], [[2i5w]], [[1yqk]], [[1yql]], [[1yqm]], [[1yqr]], [[1n39]], [[1n3a]], [[1n3c]] - hOgg1 (mutant) + DNA<BR />
**[[2nob]], [[2noe]], [[2nof]], [[2noh]], [[2noi]], [[2nol]], [[2noz]], [[2i5w]], [[1yqk]], [[1yql]], [[1yqm]], [[1yqr]], [[1n39]], [[1n3a]], [[1n3c]] - hOgg1 (mutant) + DNA<BR />
 +
**[[6rlw]] - hOgg1 + inhibitor<br />
 +
**[[1lwv]], [[1lww]], [[1lwy]] - hOgg1 + DNA<BR /> + guanine derivative<BR />
**[[1m3h]], [[3ih7]] - hOgg1 core fragment (mutant) + DNA<BR />
**[[1m3h]], [[3ih7]] - hOgg1 core fragment (mutant) + DNA<BR />
**[[1m3q]], [[1ebm]] - hOgg1 core fragment (mutant) + DNA + guanine derivative
**[[1m3q]], [[1ebm]] - hOgg1 core fragment (mutant) + DNA + guanine derivative
Line 178: Line 183:
**[[5vi0]] – PfAlkCDG + DNA – ''Pseudomonas fluorescens''<br />
**[[5vi0]] – PfAlkCDG + DNA – ''Pseudomonas fluorescens''<br />
**[[5vhv]] – PfAlkCDG + damaged DNA <br />
**[[5vhv]] – PfAlkCDG + damaged DNA <br />
- 
*Formamidopyrimidine DG
*Formamidopyrimidine DG
Line 185: Line 189:
**[[3a42]], [[3a45]] – ApFpg – ''Acanthamoeba polyphaga'' minivirus<br />
**[[3a42]], [[3a45]] – ApFpg – ''Acanthamoeba polyphaga'' minivirus<br />
**[[3twk]], [[3twl]] – AtFpg - ''Arabidopsis thaliana''<br />
**[[3twk]], [[3twl]] – AtFpg - ''Arabidopsis thaliana''<br />
 +
**[[6tc6]] – NmFpg - ''Neisseria meningitidis''<br />
 +
**[[6tc9]] – NmFpg + DNA + DNA containing abasic analog<br />
*''Fpg complex with DNA''
*''Fpg complex with DNA''
Line 219: Line 225:
**[[3jr4]] – GsFpg (mutant) + DNA + guanosine derivative <br />
**[[3jr4]] – GsFpg (mutant) + DNA + guanosine derivative <br />
-
*DNA glycosylase NEI
+
*DNA glycosylase NEI see [[Endonuclease]]-VIII
-
**[[2ea0]], [[2opf]], [[2oq4]], [[1k3w]], [[1k3x]] – EcGD NEI + DNA<BR />
 
-
**[[2fcc]] – Pyrimidine GD + DNA – Enterobacteria phage T4<br />
 
-
**[[1q39]] – EcGD NEI<br />
 
-
**[[1q3b]], [[1q3c]] – EcGD NEI (mutant)<br />
 
-
**[[1tdh]] – hGD NEI
 
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:17, 1 July 2021

3D Structures of DNA glycosylase

Updated on 01-July-2021

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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