5f2u
From Proteopedia
(Difference between revisions)
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==Structure of Fully modified farnesylated INPP5E Peptide in complex with PDE6D== | ==Structure of Fully modified farnesylated INPP5E Peptide in complex with PDE6D== | ||
| - | <StructureSection load='5f2u' size='340' side='right' caption='[[5f2u]], [[Resolution|resolution]] 1.85Å' scene=''> | + | <StructureSection load='5f2u' size='340' side='right'caption='[[5f2u]], [[Resolution|resolution]] 1.85Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5f2u]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5f2u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F2U FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CMT:O-METHYLCYSTEINE'>CMT</scene>, <scene name='pdbligand=FAR:FARNESYL'>FAR</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDE6D, PDED ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDE6D, PDED ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f2u OCA], [https://pdbe.org/5f2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f2u RCSB], [https://www.ebi.ac.uk/pdbsum/5f2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f2u ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/PDE6D_HUMAN PDE6D_HUMAN]] Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation (By similarity). |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5f2u" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5f2u" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Fansa, E K]] | [[Category: Fansa, E K]] | ||
[[Category: Isamil, S]] | [[Category: Isamil, S]] | ||
Revision as of 03:38, 2 July 2021
Structure of Fully modified farnesylated INPP5E Peptide in complex with PDE6D
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