2qvk

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==The second Ca2+-binding domain of the Na+-Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis==
==The second Ca2+-binding domain of the Na+-Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis==
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<StructureSection load='2qvk' size='340' side='right' caption='[[2qvk]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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<StructureSection load='2qvk' size='340' side='right'caption='[[2qvk]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qvk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canlf Canlf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QVK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qvk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canlf Canlf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QVK FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2dpk|2dpk]], [[2fwu|2fwu]], [[2qvm|2qvm]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2dpk|2dpk]], [[2fwu|2fwu]], [[2qvm|2qvm]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SLC8A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 CANLF])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SLC8A1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 CANLF])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvk OCA], [http://pdbe.org/2qvk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qvk RCSB], [http://www.ebi.ac.uk/pdbsum/2qvk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qvk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvk OCA], [https://pdbe.org/2qvk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qvk RCSB], [https://www.ebi.ac.uk/pdbsum/2qvk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qvk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NAC1_CANFA NAC1_CANFA]] Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores.
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[[https://www.uniprot.org/uniprot/NAC1_CANFA NAC1_CANFA]] Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Canlf]]
[[Category: Canlf]]
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[[Category: Large Structures]]
[[Category: Abramson, J]]
[[Category: Abramson, J]]
[[Category: Besserer, G Mercado]]
[[Category: Besserer, G Mercado]]

Revision as of 04:07, 2 July 2021

The second Ca2+-binding domain of the Na+-Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis

PDB ID 2qvk

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