1eqz

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[[Image:1eqz.gif|left|200px]]
[[Image:1eqz.gif|left|200px]]
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{{Structure
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|PDB= 1eqz |SIZE=350|CAPTION= <scene name='initialview01'>1eqz</scene>, resolution 2.50&Aring;
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The line below this paragraph, containing "STRUCTURE_1eqz", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND= <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>
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{{STRUCTURE_1eqz| PDB=1eqz | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eqz OCA], [http://www.ebi.ac.uk/pdbsum/1eqz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1eqz RCSB]</span>
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'''X-RAY STRUCTURE OF THE NUCLEOSOME CORE PARTICLE AT 2.5 A RESOLUTION'''
'''X-RAY STRUCTURE OF THE NUCLEOSOME CORE PARTICLE AT 2.5 A RESOLUTION'''
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[[Category: Harp, J M.]]
[[Category: Harp, J M.]]
[[Category: Timm, D E.]]
[[Category: Timm, D E.]]
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[[Category: bent dna]]
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[[Category: Bent dna]]
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[[Category: chromatin]]
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[[Category: Chromatin]]
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[[Category: chromosomal protein]]
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[[Category: Chromosomal protein]]
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[[Category: dna palindrome]]
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[[Category: Dna palindrome]]
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[[Category: dna protein complex]]
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[[Category: Dna protein complex]]
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[[Category: histone]]
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[[Category: Histone]]
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[[Category: histone fold]]
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[[Category: Histone fold]]
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[[Category: microgravity histone octamer]]
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[[Category: Microgravity histone octamer]]
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[[Category: nucleosome]]
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[[Category: Nucleosome]]
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[[Category: nucleosome core particle]]
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[[Category: Nucleosome core particle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 15:25:32 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:07:58 2008''
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Revision as of 12:25, 2 May 2008

Image:1eqz.gif

Template:STRUCTURE 1eqz

X-RAY STRUCTURE OF THE NUCLEOSOME CORE PARTICLE AT 2.5 A RESOLUTION


Overview

The 2.5 A X-ray crystal structure of the nucleosome core particle presented here provides significant additions to the understanding of the nucleosome, the fundamental unit of chromatin structure. Extensions are made to the structure of the N-terminal histone tails and details are provided on hydration and ion binding. The structure is composed of twofold symmetric molecules, native chicken histone octamer cores and the DNA palindrome, which were expected to form a perfectly twofold symmetric nucleosome core particle. In fact, the result is asymmetric owing to the binding of the DNA to the protein surface and to the packing of the particles in the crystal lattice. An analysis is made of the asymmetries by comparisons both within the nucleosome core particle and to the structure of the histone octamer core of the nucleosome.

About this Structure

1EQZ is a Protein complex structure of sequences from Gallus gallus. Full crystallographic information is available from OCA.

Reference

Asymmetries in the nucleosome core particle at 2.5 A resolution., Harp JM, Hanson BL, Timm DE, Bunick GJ, Acta Crystallogr D Biol Crystallogr. 2000 Dec;56(Pt 12):1513-34. PMID:11092917 Page seeded by OCA on Fri May 2 15:25:32 2008

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OCA

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