2rf8
From Proteopedia
(Difference between revisions)
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==Crystal Structure of the mutant C2A conjugated bile acid hydrolase from Clostridium perfringens== | ==Crystal Structure of the mutant C2A conjugated bile acid hydrolase from Clostridium perfringens== | ||
| - | <StructureSection load='2rf8' size='340' side='right' caption='[[2rf8]], [[Resolution|resolution]] 2.90Å' scene=''> | + | <StructureSection load='2rf8' size='340' side='right'caption='[[2rf8]], [[Resolution|resolution]] 2.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2rf8]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2rf8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RF8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RF8 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bjf|2bjf]], [[2bjg|2bjg]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bjf|2bjf]], [[2bjg|2bjg]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cbh ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cbh ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 Clostridium perfringens])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Choloylglycine_hydrolase Choloylglycine hydrolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.24 3.5.1.24] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rf8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rf8 OCA], [https://pdbe.org/2rf8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rf8 RCSB], [https://www.ebi.ac.uk/pdbsum/2rf8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rf8 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CBH_CLOPE CBH_CLOPE]] The enzyme catalyzes the degradation of conjugated bile acids in the mammalian gut. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Choloylglycine hydrolase]] | [[Category: Choloylglycine hydrolase]] | ||
[[Category: Clostridium perfringens]] | [[Category: Clostridium perfringens]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Rossmann, M]] | [[Category: Rossmann, M]] | ||
[[Category: Saenger, W]] | [[Category: Saenger, W]] | ||
Revision as of 04:23, 2 July 2021
Crystal Structure of the mutant C2A conjugated bile acid hydrolase from Clostridium perfringens
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