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2rgf
From Proteopedia
(Difference between revisions)
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==RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES== | ==RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES== | ||
| - | <StructureSection load='2rgf' size='340' side='right' caption='[[2rgf]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | + | <StructureSection load='2rgf' size='340' side='right'caption='[[2rgf]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2rgf]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2rgf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RGF FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HUMAN RALGEF GENE (RALGDS) ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HUMAN RALGEF GENE (RALGDS) ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rgf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgf OCA], [https://pdbe.org/2rgf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rgf RCSB], [https://www.ebi.ac.uk/pdbsum/2rgf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rgf ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/GNDS_HUMAN GNDS_HUMAN]] Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the GTPases. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Geyer, M]] | [[Category: Geyer, M]] | ||
[[Category: Herrmann, C]] | [[Category: Herrmann, C]] | ||
Revision as of 04:24, 2 July 2021
RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES
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Categories: Human | Large Structures | Geyer, M | Herrmann, C | Kalbitzer, H R | Wittinghofer, A | Ra | Ralgd | Ralgef | Ras-binding domain | Rbd

