This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2ri8
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Penicillium citrinum alpha-1,2-mannosidase complex with glycerol== | ==Penicillium citrinum alpha-1,2-mannosidase complex with glycerol== | ||
| - | <StructureSection load='2ri8' size='340' side='right' caption='[[2ri8]], [[Resolution|resolution]] 2.16Å' scene=''> | + | <StructureSection load='2ri8' size='340' side='right'caption='[[2ri8]], [[Resolution|resolution]] 2.16Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ri8]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2ri8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_1109 Atcc 1109]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RI8 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kkt|1kkt]], [[1kre|1kre]], [[1krf|1krf]], [[2ri9|2ri9]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1kkt|1kkt]], [[1kre|1kre]], [[1krf|1krf]], [[2ri9|2ri9]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MSDC ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MSDC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5077 ATCC 1109])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,2-alpha-mannosidase Mannosyl-oligosaccharide 1,2-alpha-mannosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.113 3.2.1.113] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ri8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ri8 OCA], [https://pdbe.org/2ri8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ri8 RCSB], [https://www.ebi.ac.uk/pdbsum/2ri8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ri8 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/MAN12_PENCI MAN12_PENCI]] Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 31: | Line 31: | ||
</div> | </div> | ||
<div class="pdbe-citations 2ri8" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2ri8" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Mannosidase 3D structures|Mannosidase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 36: | Line 39: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Atcc 1109]] | [[Category: Atcc 1109]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mannosyl-oligosaccharide 1,2-alpha-mannosidase]] | [[Category: Mannosyl-oligosaccharide 1,2-alpha-mannosidase]] | ||
[[Category: Claeyssens, M]] | [[Category: Claeyssens, M]] | ||
Current revision
Penicillium citrinum alpha-1,2-mannosidase complex with glycerol
| |||||||||||
Categories: Atcc 1109 | Large Structures | Mannosyl-oligosaccharide 1,2-alpha-mannosidase | Claeyssens, M | Desmet, T | Herscovics, A | Howell, P L | Lobsanov, Y D | Nerinckx, W | Yip, P | Yoshida, T | Alternative conformation | Glycoprotein | Glycosidase | Hydrolase | Modulation of activity | Secreted

