This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6s4m
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of the human organic anion transporter MFSD10 (TETRAN)== | ==Crystal structure of the human organic anion transporter MFSD10 (TETRAN)== | ||
| - | <StructureSection load='6s4m' size='340' side='right'caption='[[6s4m]]' scene=''> | + | <StructureSection load='6s4m' size='340' side='right'caption='[[6s4m]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S4M OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6s4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6S4M FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MFSD10, TETRAN ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6s4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s4m OCA], [https://pdbe.org/6s4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6s4m RCSB], [https://www.ebi.ac.uk/pdbsum/6s4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6s4m ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/MFS10_HUMAN MFS10_HUMAN]] Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump.<ref>PMID:17362938</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Bountra C]] | + | [[Category: Bountra, C]] |
| - | [[Category: Burgess-Brown | + | [[Category: Burgess-Brown, N A]] |
| - | [[Category: Bushell | + | [[Category: Bushell, S R]] |
| - | [[Category: Carpenter | + | [[Category: Carpenter, E P]] |
| - | [[Category: Chalk R]] | + | [[Category: Chalk, R]] |
| - | [[Category: Chu A]] | + | [[Category: Chu, A]] |
| - | [[Category: Edwards | + | [[Category: Edwards, A M]] |
| - | [[Category: Mukhopadhyay | + | [[Category: Mukhopadhyay, S M.M]] |
| - | [[Category: Pascoa | + | [[Category: Pascoa, T C]] |
| - | [[Category: Pike | + | [[Category: Pike, A C.W]] |
| - | [[Category: Quigley A]] | + | [[Category: Quigley, A]] |
| - | [[Category: Shrestha L]] | + | [[Category: Structural genomic]] |
| - | [[Category: Venkaya S]] | + | [[Category: Shrestha, L]] |
| + | [[Category: Venkaya, S]] | ||
| + | [[Category: Amtf1]] | ||
| + | [[Category: Membrane transporter]] | ||
| + | [[Category: Mfsd10]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Slc22a32]] | ||
| + | [[Category: Tetran]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 09:58, 14 July 2021
Crystal structure of the human organic anion transporter MFSD10 (TETRAN)
| |||||||||||
Categories: Human | Large Structures | Arrowsmith, C H | Bountra, C | Burgess-Brown, N A | Bushell, S R | Carpenter, E P | Chalk, R | Chu, A | Edwards, A M | Mukhopadhyay, S M.M | Pascoa, T C | Pike, A C.W | Quigley, A | Structural genomic | Shrestha, L | Venkaya, S | Amtf1 | Membrane transporter | Mfsd10 | Sgc | Slc22a32 | Tetran | Transport protein
