1cuk

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<StructureSection load='1cuk' size='340' side='right'caption='[[1cuk]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='1cuk' size='340' side='right'caption='[[1cuk]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1cuk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CUK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1cuk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CUK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CUK FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cuk OCA], [http://pdbe.org/1cuk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1cuk RCSB], [http://www.ebi.ac.uk/pdbsum/1cuk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1cuk ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cuk OCA], [https://pdbe.org/1cuk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cuk RCSB], [https://www.ebi.ac.uk/pdbsum/1cuk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cuk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RUVA_ECOLI RUVA_ECOLI]] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA.<ref>PMID:8433990</ref>
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[[https://www.uniprot.org/uniprot/RUVA_ECOLI RUVA_ECOLI]] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA.<ref>PMID:8433990</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 10:40, 14 July 2021

ESCHERICHIA COLI RUVA PROTEIN AT PH 4.9 AND ROOM TEMPERATURE

PDB ID 1cuk

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