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1e4j

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<StructureSection load='1e4j' size='340' side='right'caption='[[1e4j]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='1e4j' size='340' side='right'caption='[[1e4j]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1e4j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E4J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1E4J FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1e4j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E4J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E4J FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fcb|2fcb]], [[1e4k|1e4k]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2fcb|2fcb]], [[1e4k|1e4k]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e4j OCA], [http://pdbe.org/1e4j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1e4j RCSB], [http://www.ebi.ac.uk/pdbsum/1e4j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1e4j ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e4j OCA], [https://pdbe.org/1e4j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e4j RCSB], [https://www.ebi.ac.uk/pdbsum/1e4j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e4j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FCG3B_HUMAN FCG3B_HUMAN]] Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
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[[https://www.uniprot.org/uniprot/FCG3B_HUMAN FCG3B_HUMAN]] Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 09:34, 21 July 2021

Crystal structure of the soluble human Fc-gamma Receptor III

PDB ID 1e4j

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