Growth factors

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*[[Autocrine motility factor]]
*[[Autocrine motility factor]]
Rabbit <scene name='48/481605/Cv/6'>Phosphoglucose isomerase (autocrine motility factor) active site containing the substrate D-fructose 6-phosphate shows the substrate interacting mainly with residues of one subunit</scene><ref>PMID:11425306</ref>. Water molecules are shown as red spheres.
Rabbit <scene name='48/481605/Cv/6'>Phosphoglucose isomerase (autocrine motility factor) active site containing the substrate D-fructose 6-phosphate shows the substrate interacting mainly with residues of one subunit</scene><ref>PMID:11425306</ref>. Water molecules are shown as red spheres.
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*[[Bone morphogenetic protein]]
+
*[[Bone morphogenetic protein]]. For details on BMP-7 see [[Student Projects for UMass Chemistry 423 Spring 2012-4]].
*[[Colony-stimulating factor]]
*[[Colony-stimulating factor]]
*[[Epidermal growth factor]] and [[Epidermal Growth Factor Receptor]]
*[[Epidermal growth factor]] and [[Epidermal Growth Factor Receptor]]

Revision as of 13:08, 27 July 2021

Platelet-Derived Growth Factor Receptor (brown and turquoise) complex with Platelet-Derived Growth Factor B (grey and green) (PDB code 3mjg)

Drag the structure with the mouse to rotate

References

  1. Mohedas AH, Wang Y, Sanvitale CE, Canning P, Choi S, Xing X, Bullock AN, Cuny GD, Yu PB. Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants. J Med Chem. 2014 Oct 9;57(19):7900-15. doi: 10.1021/jm501177w. Epub 2014 Sep 4. PMID:25101911 doi:http://dx.doi.org/10.1021/jm501177w
  2. Lee JH, Chang KZ, Patel V, Jeffery CJ. Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate D-fructose 6-phosphate. Biochemistry. 2001 Jul 3;40(26):7799-805. PMID:11425306

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Alexander Berchansky

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