Glutamate receptor 3D structures
From Proteopedia
(Difference between revisions)
| Line 53: | Line 53: | ||
**[[4u4g]], [[6u5s]], [[6u6i]] - rIGluR2 + antagonist<br /> | **[[4u4g]], [[6u5s]], [[6u6i]] - rIGluR2 + antagonist<br /> | ||
A [[Glutamate receptor (GluA2)|topic page]] describing in detail the [[Glutamate receptor (GluA2)|GluA2 structure described in 3kg2]]<br /> | A [[Glutamate receptor (GluA2)|topic page]] describing in detail the [[Glutamate receptor (GluA2)|GluA2 structure described in 3kg2]]<br /> | ||
| - | **[[3h03]], [[3h06]], [[3b7d]], [[1n0t]], [[1ftl]], [[3tza]], [[3ua8]], [[4isu]], [[5cbs]], [[5cbr]], [[4yma]], [[6yk2]], [[6yk3]], [[6yk4]], [[6yk5]], [[6yk6]] - rIGluR2 LBD + antagonist<br /> | + | **[[3h03]], [[3h06]], [[3b7d]], [[1n0t]], [[1ftl]], [[3tza]], [[3ua8]], [[4isu]], [[5cbs]], [[5cbr]], [[4yma]], [[6xsr]], [[6yk2]], [[6yk3]], [[6yk4]], [[6yk5]], [[6yk6]] - rIGluR2 LBD + antagonist<br /> |
**[[1lb9]], [[4l17]], [[4u21]], [[4u22]], [[4u23]], [[5kbv]] - rIGluR2 LBD (mutant) + antagonist<br /> | **[[1lb9]], [[4l17]], [[4u21]], [[4u22]], [[4u23]], [[5kbv]] - rIGluR2 LBD (mutant) + antagonist<br /> | ||
| Line 76: | Line 76: | ||
*''GluR2 ligand complex'' | *''GluR2 ligand complex'' | ||
| + | **[[7f3o]] - hIGluR2 LBD + Glu + antagonist<br /> | ||
**[[3dp6]], [[2uxa]], [[2i3v]], [[2i3w]], [[1ftj]], [[4z0i]], [[4o3b]], [[6gl4]] - rIGluR2 LBD + Glu<br /> | **[[3dp6]], [[2uxa]], [[2i3v]], [[2i3w]], [[1ftj]], [[4z0i]], [[4o3b]], [[6gl4]] - rIGluR2 LBD + Glu<br /> | ||
**[[3b6q]], [[3b6w]], [[2gfe]], [[3t9x]], [[4u4s]], [[4u4x]], [[4yu0]], [[6giv]] - rIGluR2 LBD (mutant) + Glu<br /> | **[[3b6q]], [[3b6w]], [[2gfe]], [[3t9x]], [[4u4s]], [[4u4x]], [[4yu0]], [[6giv]] - rIGluR2 LBD (mutant) + Glu<br /> | ||
| Line 82: | Line 83: | ||
**[[4uqk]], [[4uqj]], [[4uq6]] - rIGluR2 + quisqualate – Cryo EM<br /> | **[[4uqk]], [[4uqj]], [[4uq6]] - rIGluR2 + quisqualate – Cryo EM<br /> | ||
**[[4wxj]] - DmIGluR2 LBD + Glu<br /> | **[[4wxj]] - DmIGluR2 LBD + Glu<br /> | ||
| + | |||
| + | *Ionotropic glutamate receptor 3.2 | ||
| + | |||
| + | **[[6x5q]] – AtIGluR3.2 LBD + Gly – ''Arabidopsis thaliana''<br /> | ||
*Ionotropic glutamate receptor 3.3 | *Ionotropic glutamate receptor 3.3 | ||
| - | **[[6r88]] – AtIGluR3.3 LBD | + | **[[6r88]] – AtIGluR3.3 LBD<br /> |
**[[6r85]] – AtIGluR3.3 LBD + Glu <br /> | **[[6r85]] – AtIGluR3.3 LBD + Glu <br /> | ||
**[[6r89]], [[6r8a]] – AtIGluR3.3 LBD + amino acid <br /> | **[[6r89]], [[6r8a]] – AtIGluR3.3 LBD + amino acid <br /> | ||
| + | |||
| + | *Ionotropic glutamate receptor 3.4 | ||
| + | |||
| + | **[[7lzi]] – AtIGluR3.4 – Cryo EM<br /> | ||
| + | **[[7lzh]] – AtIGluR3.4 + Glu – Cryo EM<br /> | ||
*Ionotropic glutamate receptor δ | *Ionotropic glutamate receptor δ | ||
| Line 98: | Line 108: | ||
**[[5cc2]] – rIGluRδ2 LBD + agonist<br /> | **[[5cc2]] – rIGluRδ2 LBD + agonist<br /> | ||
| - | *Ionotropic glutamate receptor 1+2 | + | *Ionotropic glutamate receptor 1+2 or AMPA receptor |
| - | **[[6qkz]], [[6qkc]] – rIGluR1 + rGluR2 + calcium channel | + | **[[7occ]] – rIGluR1 + rGluR2 – Cryo EM <br /> |
| - | **[[6njl]] – rIGluR1 + rGluR2 + calcium channel | + | **[[6qkz]], [[6qkc]], [[7ocd]] – rIGluR1 + rGluR2 + calcium channel γ-8 – Cryo EM <br /> |
| + | **[[7oca]], [[7ocf]] – rIGluR1 + rGluR2 + calcium channel γ-8 + CNIH2 – Cryo EM <br /> | ||
| + | **[[6njl]] – rIGluR1 + rGluR2 + calcium channel γ-8 + SCFV + auxiliary protein + antibody – Cryo EM <br /> | ||
**[[6ovd]], [[6ove]] – rIGluR1 + rGluR2 residues 415-821 + antagonist<br /> | **[[6ovd]], [[6ove]] – rIGluR1 + rGluR2 residues 415-821 + antagonist<br /> | ||
| + | **[[7ldd]], [[7lde]] – mIGluR1 + mGluR2 + calcium channel γ-8 + SCFV + antibody – Cryo EM <br /> | ||
*Ionotropic glutamate receptor 1+2+3 | *Ionotropic glutamate receptor 1+2+3 | ||
| Line 116: | Line 129: | ||
**[[5fwx]] – rIGluR2 ATD + rIGluR4 ATD <br /> | **[[5fwx]] – rIGluR2 ATD + rIGluR4 ATD <br /> | ||
| + | |||
| + | *Ionotropic glutamate receptor 1+2+3+4 | ||
| + | |||
| + | **[[7lep]] – rIGluR1 + rGluR2 + rIGluR3 + rGluR4 + calcium channel γ-8 + CNIH2 – Cryo EM <br /> | ||
*Ionotropic glutamate receptor 3 | *Ionotropic glutamate receptor 3 | ||
| Line 203: | Line 220: | ||
**[[3om0]], [[3om1]] – rGluK5 ATD<br /> | **[[3om0]], [[3om1]] – rGluK5 ATD<br /> | ||
| + | |||
| + | *Ionotropic kainate receptor 2+5 | ||
| + | |||
| + | **[[7ks3]] – rGluK2 + rGluK5 – Cryo EM<br /> | ||
| + | **[[7ks0]] – rGluK2 + rGluK5 + inhibitor – Cryo EM<br /> | ||
**[[3qlu]] - rGluK5 + rGluK2 (mutant)<br /> | **[[3qlu]] - rGluK5 + rGluK2 (mutant)<br /> | ||
**[[3qlv]] - rGluK5 + rGluK2 | **[[3qlv]] - rGluK5 + rGluK2 | ||
| + | |||
| + | |||
*NMDA receptor (NMDAR) | *NMDA receptor (NMDAR) | ||
| Line 214: | Line 238: | ||
**[[3q41]] – rNMDAR N ATD <br /> | **[[3q41]] – rNMDAR N ATD <br /> | ||
**[[1y1m]], [[1y1z]], [[1y20]] – NMDAR LBD (mutant) + partial agonist<br /> | **[[1y1m]], [[1y1z]], [[1y20]] – NMDAR LBD (mutant) + partial agonist<br /> | ||
| - | **[[2hqw]] – NMDAR C terminal + calmodulin<br /> | ||
**[[1pb7]] – rNMDAR LBD + glycine<br /> | **[[1pb7]] – rNMDAR LBD + glycine<br /> | ||
**[[1pb8]], [[1pb9]] – rNMDAR LBD + serine<br /> | **[[1pb8]], [[1pb9]] – rNMDAR LBD + serine<br /> | ||
| Line 225: | Line 248: | ||
**[[2a5s]] - rNMDAR LBD + glutamate<br /> | **[[2a5s]] - rNMDAR LBD + glutamate<br /> | ||
| - | **[[4jwx]] – rNMDAR LBD + agonist<br /> | + | **[[4jwx]], [[6odl]] – rNMDAR LBD + agonist<br /> |
*''NMDAR subunit NR2B'' | *''NMDAR subunit NR2B'' | ||
| + | **[[6xbp]] - hNMDAR 1289-1310 + CAMK2A <br /> | ||
| + | **[[7kl0]], [[7kl2]], [[7kl4]] - hNMDAR 1289-1310 (mutant) + CAMK2A <br /> | ||
| + | **[[6xdu]] - hNMDAR 1289-1310 + CAMK2A + ADP<br /> | ||
| + | **[[6xbx]] - hNMDAR 1289-1310 + CAMK2A + ATP<br /> | ||
| + | **[[6xoe]], [[7kl1]] - hNMDAR 1289-1310 (mutant) + CAMK2A + ATP<br /> | ||
**[[3jpy]], [[3jpw]] - rNMDAR ATD (mutant)<br /> | **[[3jpy]], [[3jpw]] - rNMDAR ATD (mutant)<br /> | ||
**[[5up2]], [[5uow]] - XlNMDAR + NR2A + Fab + glutamate – Cryo-EM<br /> | **[[5up2]], [[5uow]] - XlNMDAR + NR2A + Fab + glutamate – Cryo-EM<br /> | ||
| Line 252: | Line 280: | ||
*''NMDAR subunit NR1+NR2A'' | *''NMDAR subunit NR1+NR2A'' | ||
| + | **[[7eos]] – hNMDAR (mutant) – Cryo EM<br /> | ||
**[[5h8f]] – hNMDAR LBD <br /> | **[[5h8f]] – hNMDAR LBD <br /> | ||
**[[6mmx]], [[6mmw]], [[6mmv]], [[6mmu]], [[6mmt]], [[6mms]], [[6mmr]], [[6mmp]], [[6mmn]], [[6mmm]], [[6mml]], [[6mmk]], [[6mmj]], [[6mmi]], [[6mmh]], [[6mmg]], [[6mmb]], [[6mma]], [[6mm9]], [[6irh]], [[6irg]], [[6irf]], [[6ira]], [[6mm9]], [[6mma]], [[6mmb]], [[6mmg]], [[6mmh]], [[6mmi]], [[6mmj]], [[6mmk]], [[6mml]], [[6mmm]], [[6mmn]], [[6mmp]], [[6mmr]], [[6mms]], [[6mmt]], [[6mmu]], [[6mmv]], [[6mmw]], [[6mmx]] – rNMDAR – Cryo EM <br /> | **[[6mmx]], [[6mmw]], [[6mmv]], [[6mmu]], [[6mmt]], [[6mms]], [[6mmr]], [[6mmp]], [[6mmn]], [[6mmm]], [[6mml]], [[6mmk]], [[6mmj]], [[6mmi]], [[6mmh]], [[6mmg]], [[6mmb]], [[6mma]], [[6mm9]], [[6irh]], [[6irg]], [[6irf]], [[6ira]], [[6mm9]], [[6mma]], [[6mmb]], [[6mmg]], [[6mmh]], [[6mmi]], [[6mmj]], [[6mmk]], [[6mml]], [[6mmm]], [[6mmn]], [[6mmp]], [[6mmr]], [[6mms]], [[6mmt]], [[6mmu]], [[6mmv]], [[6mmw]], [[6mmx]] – rNMDAR – Cryo EM <br /> | ||
| Line 260: | Line 289: | ||
**[[5tpa]], [[5tp9]] – hNMDAR LBD + antagonist<br /> | **[[5tpa]], [[5tp9]] – hNMDAR LBD + antagonist<br /> | ||
| + | **[[7eoq]], [[7eot]] – hNMDAR (mutant) + antagonist – Cryo EM<br /> | ||
**[[5kdt]], [[5kcj]] – hNMDAR LBD + modulator<br /> | **[[5kdt]], [[5kcj]] – hNMDAR LBD + modulator<br /> | ||
**[[5tpa]], [[5tp9]], [[5kdt]], [[5kcj]], [[5i2n]], [[5i2k]], [[5h8q]], [[5h8n]], [[5h8h]] – hNMDAR LBD + allosteric modulator<br /> | **[[5tpa]], [[5tp9]], [[5kdt]], [[5kcj]], [[5i2n]], [[5i2k]], [[5h8q]], [[5h8n]], [[5h8h]] – hNMDAR LBD + allosteric modulator<br /> | ||
Revision as of 07:37, 9 August 2021
3D structures of glutamate receptor
Updated on 09-August-2021
A topic page describing in detail the GluA2 structure described in 3kg2
