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1jjh
From Proteopedia
(Difference between revisions)
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<StructureSection load='1jjh' size='340' side='right'caption='[[1jjh]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='1jjh' size='340' side='right'caption='[[1jjh]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1jjh]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJH OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[1jjh]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JJH FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1by9|1by9]], [[2bop|2bop]], [[1f9f|1f9f]], [[1jj4|1jj4]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1by9|1by9]], [[2bop|2bop]], [[1f9f|1f9f]], [[1jj4|1jj4]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jjh OCA], [https://pdbe.org/1jjh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jjh RCSB], [https://www.ebi.ac.uk/pdbsum/1jjh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jjh ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/VE2_BPV1 VE2_BPV1]] E2 regulates viral transcription and DNA replication. Binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. Can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</div> | </div> | ||
<div class="pdbe-citations 1jjh" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 1jjh" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Regulatory protein E2|Regulatory protein E2]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 06:41, 11 August 2021
E2 DNA-binding Domain from Bovine Papillomavirus Type 1
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